| | | 6/21/16 | 3 | 1/4 | | of injection ----+---+---+------------+-------+------+---------------+-------------- 11 | 30| ♀ | 6/11/16 | 1 | 20 |Considerable; |Considerable | | | | |minims| not so much | pain and | | | 6/12/16 | 2 | 20 | | tenderness on | | | | |minims| | palpation | | | | | | | over area | | | 6/13/16 | 1 | 25 |Not much pain |Indurated area | | | | |minims| | at pt. of | | | | | | | each. | | | | | | | Painful | | | 6/14/16 | 1 | 25 |Not much pain |Slight indura- | | | | |minims| | tion ----+---+---+------------+-------+------+---------------+-------------- * The diagnosis in Case 5 was primary syphilis, and in the other cases, secondary syphilis. † In this column, ♂ indicates male, and ♀ female. In no case did Wassermann become negative. The criticism may be raised that the number of cases and of injections is too small to permit the drawing of any just conclusions. Even should we grant it, the statistics certainly do not prove any marked superiority of any one of the preparations over the others. We wish to thank Dr. Sollmann for advising and directing us in this work, and Drs. Bailey, Bernstein, Markus and Reycraft for assistance in carrying it out. Report of Dr. Albert Keidel Twenty cases were chosen at random from the syphilitic patients attending the clinic. They were given intramuscular injections of the three solutions, in amounts varying from 1 to 2 c.c., at intervals (in most instances) of two days. The injections were invariably made into the gluteal muscles, at depths of from 2 to 2-1/2 inches, and ordinary care exercised to preserve asepsis. After injection the patient was allowed to depart, and the result was recorded at the succeeding visit. The result was determined from the patient’s statement and our examination. Some patients received injections of only one solution; some were treated with first one and later with another, and one patient received all three at different times. The solutions were never mixed for a single injection, of course. TABLE 2.--REACTIONS IN TWENTY CASES REPORTED BY DR. KEIDEL