The Propaganda for Reform in Proprietary Medicines, Vol. 2 of 2Council on Pharmacy and Chemistry (American Medical Association)
Science
The Propaganda for Reform in Proprietary Medicines, Vol. 2 of 2
Council on Pharmacy and Chemistry (American Medical Association)
Patent medicines
In reply to a request sent the Medical Supply Company for the
quantitative composition and chemical formula of the compound
“Merco-Arseno-Benzo-Chloride” and for the details of the biologic test
by which its toxicity is claimed to have been determined and evidence
for its efficiency, the following statement was received:
“Tri-Arsenole No. 1 equals to each Ampoule, gr.
Sodium chlorid 4-1/2
Hydrarg chlor.-cor. 1/4
Arsenous acid 1/4
Sodium benzoate 4
Hydrastin (resinoid) 2
Tri-Arsenole No. 2 equals to each Ampoule,
Sodium chlorid 4
Hydrarg chlor.-cor. 1/2
Arsenous acid 1/2
Sodium benzoate 4
Hydrastin (resinoid) 2
Tri-Arsenole No. 3 equals to each Ampoule,
Sodium chlorid 3-1/2
Hydrarg chlor.-cor. 3/4
Arsenous acid 3/4
Sodium benzoate 4
Hydrastin (resinoid) 2
Tri-Arsenole No. 4 equals to each Ampoule,
Sodium chlorid 3
Hydrarg chlor.-cor. 1
Arsenous acid 1
Sodium benzoate 4
Hydrastin (resinoid) 2
The request for information regarding the animal experiments said to
have determined the toxicity was ignored, nor were references supplied
to clinical reports demonstrating the value of the product.
The Council declared Tri-Arsenole inadmissible to New and Nonofficial
Remedies because of conflict with the rules as follows:
In the absence of details of the method used, the claim that the
preparation has been tested biologically is in conflict with Rule 2,
which requires that for preparations claimed to be physiologically
standardized the method of testing must be published so as to permit of
control by independent investigators.
The claims that “Merco-Arseno-Benzo-Chloride” is “the result of many
years research,” that its “toxicity has been fully tested upon animals
before using clinically” and that clinical use has “proven such
complete success” have not been substantiated by evidence and must be
held as unwarranted.
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