The statement in the letter of Fairchild Bros. and Foster “The long established custom of the use of mixtures of remedial agents rests on considerations well known and generally accepted” might well be paraphrased to read: The one-time prevalent custom of using ill-considered combinations of remedial agents has been thoroughly discredited and is generally abandoned by progressive practitioners. Such arguments as that “laxatives, tonics, carminatives, diuretics are combined with distinct advantage” have led to the use of irrational mixtures such as the compound syrup of hypophosphites and the electuary of theriaca. The Council is confident that no one who has studied the causes and treatment of digestive disorders will find occasion to prescribe at one time all the ingredients stated to be contained in Carminzym, and certainly not in the fixed proportions present therein. The comments in the Council’s report concerning ipecac certainly does apply to all active therapeutic agents. Ipecac was mentioned in the report because the several constituents of Carminzym were under discussion and hence it was necessary to point out the futility of the small dosage of ipecac in this mixture. The announcement that “Carminzym has proved of constantly increasing service” is not convincing. The Council does not know of a single clinical study of the action of Carminzym under conditions which would have afforded satisfactory evidence of its therapeutic value.--(_From The Journal A. M. A., Sept. 28, 1918._) PHILLIPS’ PHOSPHO-MURIATE OF QUININE COMP. Report of the Council on Pharmacy and Chemistry The following report on Phillips’ Phospho-Muriate of Quinine Comp. has been adopted by the Council and authorized for publication. W. A. Puckner, Secretary. Phillips’ Phospho-Muriate of Quinine Comp.[125] is sold by the Charles H. Phillips Chemical Co., New York. According to the published formula, each fluidram contains: Phosphoric Acid 2 minims Potassium Phosphate } Magnesium Phosphate } Calcium Phosphate } 2-1/4 grains Ferric Phosphate } Quinin Muriate (equal to nearly 1/2 gr. Bi-Sulph.) 1/4 grain Strychnin 1/120 grain Flavoring, Glycerin and Syrup, _q. s._