The Propaganda for Reform in Proprietary Medicines, Vol. 2 of 2Council on Pharmacy and Chemistry (American Medical Association)
Science
The Propaganda for Reform in Proprietary Medicines, Vol. 2 of 2
Council on Pharmacy and Chemistry (American Medical Association)
Patent medicines
Again the contention that formaldehyd in the nascent or active
condition is less poisonous and irritating than in its ordinary form is
contrary to what would be expected from the behavior of such compounds.
If it were liberated, as claimed, in the “nascent” condition, it would
be, for that very reason, not only more active but also more harmful.
As a matter of fact, Formamint did have an irritant effect on the
worker who carried out these investigations. When one tablet was
taken each hour for twelve consecutive hours, marked irritation of
the intestinal tract resulted. There was almost sufficient nausea to
cause vomiting and uneasiness in the alimentary canal following the
experiment. When the twenty-four tablets were taken the results were
similar but more pronounced. This is decidedly in contradiction to the
assertions of the manufacturers.
Otto Seifert,[26] moreover, cites the following:
“By Effects: Only a few patients complain of an unpleasant sharp
taste, burning of the tongue (Seifert, Sklarek). Among the general
symptoms observed are urticaria-like exanthems (Glaser, Roters),
which are accompanied by nausea, vomiting, headache, insomnia
and vertigo, burning and irritability especially in the larynx
(Meissner); phenomena of poisoning (Geissler); gastric disturbances
(Engelmann); renal irritation (Steinhard); unsuited for diabetics
(Voit).”
[26] Seifert, Otto: Die Nebenwirkungen der modernen Arzneimittel, 1915.
The contention that Formamint, when mixed directly with mediums
and left in contact with bacteria, will kill the organisms was
corroborated. Thus the statements and pictures in the booklet, “The
Gospel of Prevention,” which is enclosed with each bottle of Formamint,
showing the inhibition of growth of air bacteria on plates containing
Formamint are no doubt true and authentic.
Finally, the claim that Formamint is an almost perfect throat
disinfectant was by no means confirmed, as a glance at the tables will
show. One hour after it is taken, even when a tablet was used each
half hour for twelve hours, the number of bacteria in the throat was
practically the same as when Formamint was not used. Even ten minutes
after taking a tablet the number of bacteria in the throat was never
greatly reduced, as is maintained by the manufacturers.
HAS NO SELECTIVE ACTION
Formamint exerts no selective action in killing off the very delicate
organisms which are more apt to be pathogenic. When the comparative
counts were made on blood agar which would favor the growth of the
delicate parasitic organisms, no reduction whatever was shown by the
use of Formamint.
The number of streptococci was found to be the same, within limits of
experimental error, ten minutes after taking a tablet as it was before
the tablet was taken.
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