It is superfluous to say that we consider pleasure, for the same reasons as pain, to be an additional phenomenon, a symptom, a sign, a mark, denoting the satisfaction of certain tendencies; and that it cannot be regarded as a fundamental element of the life of the feelings. Like pain, pleasure is separable from the complex of which it forms part, and under certain abnormal conditions may totally disappear. _Anhedonia_ (if I may coin a counter-designation to analgesia) has been very little studied, but it exists. I need not say that the employment of anæsthetics suppresses at the same time pain and its contrary; but there are cases of an insensibility relating to pleasure alone. “The sensation of sexual pleasure is, in very rare cases, subject to lesions affecting no other part of the organism. Brown-Séquard saw two cases of special sexual anæsthesia, all other kinds of sensibility, those of the urethral mucous membrane and the skin, still persisting. Althaus quotes another case. It would no doubt be possible to find such cases in larger numbers were it not for the false modesty which prevents patients from speaking of the subject. Fonssagrives cites a very remarkable example observed in a woman.”[35] This insensibility exists not only for physical but also for moral pleasure (joy, high spirits, etc.). Apart from the cases of profound melancholy, which will occupy us later on, where the individual is untouched by the slightest impulse of joy, there are cases of anhedonia which seem simpler and clearer. “Antoine Cros mentions the case of a patient, a young girl, suffering from congested liver and spleen, which of course altered the state of her blood, and thus, for a time, modified her constitution. Her moral character was greatly altered by it. She ceased to feel any affection for father or mother; would play with her doll, but could not be brought to show any delight in it; could not be drawn out of her apathetic sadness. Things which previously had made her shriek with laughter now left her uninterested. Her temper changed, became capricious and violent.”[36] Esquirol has recorded the case of a magistrate, a very intelligent man, suffering from a liver complaint. “Every affection seemed to be dead in him. He showed neither perversion nor violence, but there was complete absence of emotive reaction. If he went to the theatre (as he continued to do from force of habit) he could find no pleasure there. Thoughts of his house, his home, his wife, his absent children, affected him no more, he said, than a theorem of Euclid.” We have here a specimen of what we may call a purely intellectual existence—that of the Wise Man of the Stoics. Footnote 35: Richet, _Recherches_, etc., p. 212. Footnote 36: Lewes, _Physical Basis of Mind_, p. 327.