The destroyed villages and hamlets lay thick on either bank, and the steamer wove its course diagonally from side to side calling the people to the boat, finding a committee to receive and distribute, and learning as nearly as possible the number of destitute persons, put off the requisite quantity of clothing and coal, and steamed away quickly and quietly leaving sometimes an astonished _few_, sometimes a _multitude_ to gaze after and wonder who she was, whence she came, what that strange flag meant, and most of all, to thank God with tears and prayers for what she brought. In this manner the Red Cross proceeded to Cairo, a distance of four hundred miles, where the Ohio joins the Mississippi River, which latter at that time had not risen and was exciting no apprehension. Returning, we revisited and resupplied the destitute points. The government boats running over the same track were genial and friendly with us, and faithful and efficient in their work. It should be said that, notwithstanding all the material we had shipped and distributed, so abundant had been the liberality of the people that on our return to Evansville we found our supply greater than at any previous time. At this moment, and most unexpectedly, commenced the great rise of the Mississippi River, and a _second_ cry went out to the government and the people for instant help. The strongest levees were giving way under the sudden pressure, and even the inundation of the city of New Orleans was threatened. Again the government appropriated money, and the War Department sent out its rescue and ration boats, and again the Red Cross prepared for its supplemental work. In an overflow of the Mississippi, owing to the level face of the country and the immense body of water, the valley is inundated at times thirty miles in width, thus rendering it impossible to get animals to a place of safety. Great numbers drown and the remainder, in a prolonged overflow, have largely starved, the government having never included the domestic animals in its work of relief. This seemed an omission of vital importance, both humanely and economically considered, and the Red Cross prepared to go to the relief of the starving animals of the Mississippi valley. It would also supply clothing to the destitute people whom the government would feed. The navigation of the Mississippi River calls for its own style of boats and pilotage, the latter being both difficult and dangerous, especially with the changed channels and yawning crevasses of a flood.