During the winter the lecture room was crowded with persons of the first distinction and fashion, as well as by those who had individually contributed much to the promotion of science, and although the northern accent, which he still retained in a slight degree, rendered his voice somewhat inharmonious to a London audience, his modest and unaffected manner of delivering his opinions, his familiar and at the same time elegant language rendered him the object of almost universal kindness and approbation. Dr. Garnett left Glasgow with the expectation that he should have accommodation for his family in the house of the Institution, and the first disappointment he met with was the opposition to his wishes in this respect. When he gave up his position in Glasgow he fully intended to enter into practice as a physician in London, but from this also he was restrained in great measure by the managers of the Institution. His biographer says: The exertions of the winter in some degree injured his health, and the uncertainty he saw in his prospects tended greatly to depress his spirits. He determined, however, to keep his place at the Institution. In the summer he rejoined his children in Westmoreland, but his anxiety of mind was not diminished or consequently his health improved by the relaxation from active employment. He walked over the same ground and viewed the same prospects that he had formerly enjoyed in the company of his wife. He had not resolution to check the impressions as they arose, and thus, instead of being solaced by the beauties which surrounded him, he gave the reins to his melancholy fancy, which, unchecked by any other remembrance, dwelt only on the affection and virtues of her whose loss he had ever to deplore, the want of whose society he imagined to be the chief source of his misery. Dr. Garnett showed his own position when he answered the application of Webster for his recommendation as chemical operator. Kirkby-Lonsdale, September 27, 1800.