The moment a bubo appears, take a purge, No. IX. rub the part in the groin with _mercurial ointment_, and spread a _mercurial plaister_ the bigness of a crown-piece, which, (the hair being removed,) lay on the part; let it remain on, till it separates from the skin, and the swelling is dispersed; the patient should be kept warm, and not have much exercise; at the same time the body should be kept open. By this means the bubo will soon disperse, and the virus be destroyed in its first bud. But if it has already gained too much head to be dispersed, and matter is formed, it becomes larger and soft, and a fluctuation of matter is felt, then suppuration must be promoted; and when ripe be opened as soon as possible, for an outlet of the matter. When it is come to its maturity, (that is the matter plainly perceived,) open it and dress it like an ulcer, first with the ointment, No. I. and when it discharges pretty well, dress it with the ointment, No. XXII. By this management, though easy, you will not fail of success. _Of Swelled Testicles._ The venereal virus is liable to attack the testicles, which makes one of the most disagreeable circumstances of all venereal diseases; sometimes one, and sometimes both will be the seat of this complaint. It begins with a heavy dull pain, attended with a disagreeable tightness in the spermatic vessels, leading from the testicle into the bowels. Gradually the testicle swells, becomes hard and grows very painful, and if not timely remedied, a suppuration, or a scirrhus, or even a gangrene and sphacelus, may be the consequences. The moment the pain in the testicles is perceived, remove the hair all round the scrotum, and apply a mercurial plaister spread upon leather; over which put a suspensorium, and tie it up to the body as tight as it can be borne; which together with a purge, No. IX. will not fail of giving immediate relief. The patient should be kept as quiet as possible; for hard labour not only retards the cure, but becomes very painful. Should this not be sufficient, apply the poultice, No. II. with the mercurial addition as warm as sufferable, and repeat it as often as it is necessary for keeping it warm to the part. By this method it will not fail of dispersing. Should it however against all expectation come to a suppuration, it must be opened the same as another aposthume, and treated accordingly. But should a scirrhus, or a mortification ensue, extirpation is the only recourse. For which see my treatise. _Of Venereal Excrescences._ Besides all these disorders before mentioned that are the consequence of impure coition, there is one more to be mentioned, and that is a variety of disagreeable excrescences, which sometimes arise about the penis, the scrotum perinæum, and about the fundament. When these appear, I generally take it for granted, that the pox is in the blood, and the patient ought to be treated accordingly.