or bitumen and Christ’s thorn in like manner, or a decoction of Christ’s thorn; or two drachms of dried weasel with wine, which is a cried-up remedy; or the blood of the sea-tortoise, or a drachm of castor with diluted wine, or a drachm of frankincense, or of Sicyonian root, or the juice of leeks, or ground pine, or alsander, or cinnamon, or birthwort, or the seed of the chaste tree, or cypress balls, or seseli, or pepper, or the seed of trefoil, or bay berries, or river crabs roasted or boiled. Use the following compound theriac. _A theriac for venomous animals, and deleterious substances, and for persons bitten by vipers and scorpions._ Of bryony, of opoponax, of Illyrian iris, of the root of rosemary, of ginger, of each, dr. iv; of birthwort, dr. v; of frankincense, of wild rue, of each, dr. iij; of the flour of tares, dr. ij; form trochisks with wine, and give three oboli with wine. Purging will also be proper for them, with sudorifics, and taking the theriac of vipers. * * * * * COMMENTARY. These general directions are mostly taken from Dioscorides, who is greatly indebted to Nicander. Neither of them, however, makes mention of venesection among his remedies. The remedial means recommended by Dioscorides are scarification, cupping, sucking, excision; and in extreme cases, amputation; clysters, and acrid applications to the part in order to clear out the venom; pure wine, must, or acrid substances to extinguish it and counteract its effects; and finally as adjuvants of these means, purging of the bowels, sweating, and some other particular remedies as stated under their proper heads. The general remedies mentioned by Nicander are, sucking the wound, applying cupping instruments to it, and afterwards strong stimulants, hot irons, and leeches. He directs that the person who sucks it should not be fasting; from which it may be inferred that he had a correct idea that the vessels absorb most readily when in an empty state. This physiological doctrine was lately announced as a new discovery; but frequent allusions to it are to be met with in the works of Galen, our author, Avicenna, Avenzoar, Averrhoes, and Haly Abbas. The dangers resulting from an empty state of the vessels, whether produced by fasting or venesection, is well expressed by Gorræus in his Preliminary Dissertation on the Alexipharmics of Nicander: “Nec vero id tantum incommodi habet fames, sed in multo majus periculum adducit hominem, quando et venæ plurimum exinanitæ et cibum vehementer appetentes, venenum avidius ad se pertrahunt et in intima viscera, cordisque arcem immittunt.” “Quod si quis etiam abundare videatur, et nihil eorum repugnet quæ sunt in venæsectione observanda, sanguinem audacter mittamus, non quidem per initia (sic enim in venas deleteria traherentur, a quibus omni studio atque industriâ excludi debent) sed post vomitus alvique dejectiones,” &c.