The most grievous symptoms follow the administration of cantharides, for almost from the mouth to the bladder the parts are tormented with a gnawing pain. The taste resembles pitch or cedar rosin, and the patients have inflammation of the right hypochondrium, with dysuria, and frequently they pass blood by urine, and sometimes it is discharged by the intestines, as in dysentery: they fall into deliquium animi, nausea, and vertigo, and at last they become delirious. The proper remedies are vomiting with water and oil, drinking milk, taking four drachms of Cimolian earth with honied water, pine kernels, the seeds of cucumber, fat beef soup, or soup of geese or of mutton; the flesh of fowls, lambs, sheep, or pigs, being tender and fat, when boiled with linseed; much must; dr. iv of the bark of rosemary; and after the food inject by clyster the juice of rice, or of chondrus, or of spelt, or of ptisan, or of mallows, or of linseed, or of marshmallows, or of fenugreek. And sometimes having cleared out the intestine with honied water and nitre, we may then inject these things, and afterwards allay the inflammation with cataplasms of linseed and barley; for at first these things are pernicious. Then we may have recourse to baths of sweet water, and give the ointments of iris and of roses in a draught. * * * * * COMMENTARY. The symptoms occasioned by taking cantharides, according to Nicander, are erosion of the whole intestinal canal, ulceration of the bladder, affection of the chest, and wild delirium. His remedies are emetics, such as fat, the oil of iris with rue, or Samian aster, laxatives, milk in clysters or taken by the mouth, and the decoction of vine-shoots with honey. Dioscorides describes the symptoms in the same terms as our author, and like him recommends emetics of oil and emollient clysters, such as the decoction of linseed or of mallows. Like our author, he disapproves of warm applications, such as cataplasms and the hot bath at the commencement, because by their heat they promote the distribution of the poison over the system; but after a time they are useful, he says, by allaying the pains and promoting the discharge of the poison by the cutaneous perspiration. His other remedies being the same as our author’s, we need not enumerate them. Galen states that the wings and feet of cantharides prove useful for removing the deleterious effects occasioned by taking their bodies. His treatment otherwise, which is borrowed from Asclepiades, is very similar to that of Dioscorides. He in particular recommends the Lemnian earth, or terra sigillata, as an emetic in this case. (De simpl. ix.) He also speaks favorably of milk. (Ib. and de antidot. ii.) He approves very much of animal and vegetable oils given in sweet wine or tepid water to produce vomiting. Galen states decidedly that the viscus upon which the action of cantharides is exerted is the bladder. (Ad Pison.) The treatment recommended by