COMMENTARY. Sulphur was extensively used in medicine from the earliest times. Pliny gives a very full and interesting account of it. (H. N. xxxv, 50.) The sulphur vivum, of which mention is so often made in this work, was evidently native sulphur, that is to say, the prismatic sulphur of Jameson. The sulphur ignem expertum was clearly the factitious sulphur or brimstone, namely, that which is procured from pyrites by sublimation. We need scarcely mention that sulphur was extensively used as an application in cutaneous diseases, and more especially scabies. It was also given internally in catarrhs and other complaints of the chest. See Dioscorides and Pliny. The words of the latter are well worth quoting in the present instance. “Natura ejus calfacit, concoquit, sed et discutit collectiones corporum: ob hoc talibus emplastris malagmatisque miscetur. Renibus quoque et lumbis in dolore cum adipe mire prodest impositum. Aufert et lichenas a facie cum terebinthi resina et lepras. Harpacticon vocatur a celeritate avellendi, avelli enim subinde debet. Prodest et suspiriosis linctum. Purulenta quoque extussientibus, et contra scorpionum ictus. Vitiligines vivum nitro mixtum atque ex aceto tritum et illitum tollit, item lendes in palpebris, aceto sandarachato admixto.” We have not found the acetum sandarachatum mentioned by any other writer; from its name, it was no doubt composed of vinegar and arsenic, that is to say, realgar. Serapion, in treating of sulphur, confines himself entirely to Greek authorities (407); and so in like manner Avicenna (ii, 2, 612), and Rhases (Cont. ult. 694.) Θέρμος, Lupinus, _Lupine_; that which is edible is possessed of emplastic powers; but the bitter is detergent, discutient, and desiccative, without pungency. It kills worms, both when applied externally and when taken in infusion, and it cleanses the bowels when drunk with rue and pepper. It also cleanses the skin, and discusses tumours when applied with oxymel. The wild is more bitter and stronger than the cultivated in all respects. * * * * *