But the year A.D. 341 saw a change. Sapor, after obtaining possession of the person of Tiranus, had sought to make himself master of Armenia, and had even attempted to set up one of his own relatives as king. But the indomitable spirit of the inhabitants, and their firm attachment to their Arsacid princes, caused his attempts to fail of any good result, and tended on the whole to throw Armenia into the arms of Rome. Sapor, after a while, became convinced of the folly of his proceedings, and resolved on the adoption of a wholly new policy. He would relinquish the idea of conquering, and would endeavor instead to conciliate the Armenians, in the hope of obtaining from their gratitude what he had been unable to extort from their fears. Tiranus was still living; and Sapor, we are told, offered to replace him upon the Armenian throne; but, as he had been blinded by his captors, and as Oriental notions did not allow a person thus mutilated to exercise royal power, Tiranus declined the offer made him, and suggested the substitution of his son, Arsaces, who was, like himself, a prisoner in Persia. Sapor readily consented; and the young prince, released from captivity, returned to his country, and was installed as king by the Persians, with the good-will of the natives, who were satisfied so long as they could feel that they had at their head a monarch of the ancient stock. The arrangement, of course, placed Armenia on the Persian side, and gave Sapor for many years a powerful ally in his struggle with Rome. Thus Sapor had, by the, year A.D. 341, made a very considerable gain. He had placed a friendly sovereign on the Armenian throne, had bound him to his cause by oaths, and had thereby established his influence, not only over Armenia itself, but over the whole tract which lay between Armenia and the Caucasus. But he was far from content with these successes. It was still his great object to drive the Romans from Mesopotamia; and with that object in view it continued to be his first wish to obtain possession of Nisibis. Accordingly, having settled Armenian affairs to his liking, he made, in A.D. 346, a second attack on the great city of Northern Mesopotamia, again investing it with a large body of troops, and this time pressing the siege during the space of nearly three months. Again, however, the strength of the walls and the endurance of the garrison baffled him. Sapor was once more obliged to withdraw from, before the place, having suffered greater loss than those whom he had assailed, and forfeited much of the prestige which he had acquired by his many victories.