repetitions of the operation of blowing the nose.[13] A correspondent of the “Petersburg (Va) Express” says:——“There are, perhaps, in our state 125,000 women, leaving out of the account those who have not cut their teeth, and those who have lost them from age. Of this number, eighty per cent. may be safely set down as snuff-dippers. Every five of these will use a two-ounce paper of snuff per day—that is to the 100,000 dippers 2,500 lbs. a day, amounting to the enormous quantity of 912,000 lbs. In this number of snuff-dippers are included all ages, colours, and conditions. This practice is generally prevalent in the pine districts of North Carolina, and in many parts of South Carolina, Georgia, Alabama, Florida, and Eastern Tennessee. It may be thus described:—A female snuff-dipper takes a short stick, and, wetting it, dips it into her snuff-box, and then rubs the gathered dust all about her mouth, into the interstices of her teeth, &c., where she allows it to remain until its strength has been fully absorbed. Others hold the stick thus loaded with snuff in the cheek, _à la_ quid of tobacco, and suck it with a decided relish, while engaged in their ordinary avocations; while others simply fill the mouth with the snuff, and thus imitate, to all intents and purposes, the chewing propensities of the men. In the absence of snuff, tobacco, in the plug or leaf, is invariably resorted to as a substitute. Oriental betel chewing is elegant, compared tosnuff-dipping.” The most uncomfortable reflection to the snuffer is that which concerns the probability of his consuming himself by a condition of slow poisoning, not the result of the pure tobacco, but its impure associates in the box. In boxes lined with very thin lead, but especially in cases where the leaden lining is thicker, and which are much used by the Paris retailers, a chemical action takes place, the result of which is to charge the snuff with sub-acetate of lead. This result was suspected by Chevalier, and has been confirmed by Boudet of Paris, and Mayer of Berlin, by careful experiments. Mayer traces several deaths and cases of saturnine paralysis to the patient’s having taken snuff from packets, the inner envelope of which was thin sheet lead, in constant contact with the powdered weed. The cry once heard of “death in the pot,” requires now to be exchanged for “death in the box,” and Holbein to give us a new plate of the skeleton form emerging from a packet or snuff-box containing the scented rappee.