Was infected with Horsegrease in the same way as Pearce. Some years afterwards was inoculated with Smallpox, but only a few eruptions appeared on his forehead, which passed away without maturation. XV.--ABRAHAM RIDDIFORD, Farmer. Was affected with very painful sores in both hands, tumours in each arm-pit, and severe and general indisposition, in consequence of dressing a Mare that had sore heels. He was attended by a surgeon, who recognising a similarity of the sores upon his hands with those of Cowpox, and knowing the effect of Cowpox on the human constitution, assured him that he never need fear Smallpox; but, twenty years afterwards, he caught the disease, which ran its regular course. From these Cases Jenner drew this conclusion-- Although the absorption of matter from sores on the heels of Horses, secures, or nearly secures, the system from variolous infection, yet it is possible that this cannot be entirely relied upon, until a disease has been generated by morbid matter from the Horse on the nipple of the Cow, and passed through that medium to the human subject. Which conclusion he repeated thus-- The active quality of the virus from the Horse’s heels is greatly increased after it has acted on the nipples of the Cow; as it rarely happens that the Horse affects his dresser with sores; and as rarely that a milkmaid escapes infection when she milks infected Cows. (P. 45.) From this conclusion, Jenner at a subsequent period withdrew. The virus from the Horse was employed for inoculation without transmission through the Cow, and with results equally satisfactory. As we shall find, Jenner used and distributed Equine Virus neat, which he certified as “the true and genuine life-preserving fluid.” So far the Cases set forth described no more than ordinary Gloucestershire experience; but we now come upon ground regarded as peculiarly Jennerian. XVI.--SARAH NELMES, Dairymaid. In 1796 was infected with Cowpox, receiving the virus on a part of her hand scratched by a thorn. From the large pustulous sore on Sarah’s hand Jenner, on the 14th May, inoculated-- XVII.--JAMES PHIPPS, eight years old. Said Jenner, “The more accurately to observe the progress of the infection, I selected a healthy boy, about eight years old, for the purpose of INOCULATION FOR THE COWPOX.” The matter was inserted into his arm by two incisions, barely penetrating the cutis, each about half an inch long. The inoculation “took,” and was followed by a chill, loss of appetite, headache, and restless sleep. On the 1st of July, the poor lad was inoculated with Smallpox, and again several months afterwards, it is said, without effect.