He preferred to be adjudged mistaken rather than risk the forfeit of public favour and pay. Nor might I blame him, had he frankly reasserted the integrity of the Gloucestershire faith, and allowed that since the public were ready to accept Cowpox without Horsegrease, it was not for him to stand in the way of their preference by an obstinate defence of what was non-essential in practice. But the case for Horsegrease was yet stronger than I have stated. Dr. Sacco of Milan was sometimes described as “the prince of vaccinators” by reason of his enthusiasm, his professional attainments, and the facilities that were accorded to him in the Cisalpine Republic of those days for universal vaccination. He tried to generate pox on the cow with grease from the horse, but failed, and in 1801 reported to Jenner his failure. In 1803, however, he cried, Eureka! A coachman presented himself at the Milan Hospital suffering from an eruption contracted in grooming a horse with greasy heels. He was at once led off by Sacco to the Foundling Asylum, where nine children were inoculated from the vesicles on his hands. On three of the children the inoculation took, producing vesicles which were pronounced to be the same as those resulting from Cowpox. The virus was propagated from arm to arm, and distributed in all directions. Dr. Sacco from thenceforth avowed himself a Horsegreaser. “It is now admitted and settled,” he wrote to Jenner from Milan, 25th March, 1803, “that grease is the cause of vaccine, and we cannot too soon alter the designation to equine.” Was the designation changed to equine? It was not, nor was the attempt made. Those chiefly concerned in promoting vaccination in England would not hear of Horsegrease, and many were ready to swear that in the matter of pox, the horse and the cow had no connection whatever, and that Jenner had too hastily assumed the truth of a vulgar west country opinion. Dr. De Carro of Vienna, who described himself as Jenner’s friend and first apostle, having effected the first vaccination on the Continent and transmitted the first charge of vaccine to India, was also a Horsegreaser. Whilst Jenner was judiciously holding his tongue about Horsegrease in England, he wrote to De Carro congratulating him on his success in conveying Cowpox to the East, and ascribing the failure of the English attempts to the absurd prejudice against Horsegrease, which Dr. Loy had, however, completely annihilated. Here are his words under date, 28th March, 1803-- I am confident that had not the opponents of my ideas of the origin of the disease been so absurdly clamorous, particularly the _par nobile fratrum_ [Pearson and Woodville], the Asiatics would long since have enjoyed the blessings of Vaccination, and many a victim been rescued from an untimely grave. The decisive experiments of Dr. Loy have silenced the tongues of these gentlemen for ever.[146]