It may be well to devote a chapter to those antagonists of Vaccination who, though right in their contention against cowpox, did more or less to discredit their cause by scurrility and extravagance. The faults of these men are frequently adduced as evidence of the absurd and brutal resistance with which Vaccination was encountered, but it is forgotten how intense was their provocation, and how the bad on one side was matched by the bad on the other. It was a contest between Smallpoxers and Cowpoxers, alike ignorant of the conditions of physical well-being. It is plain, however, in the light of our later experience, that much that was asserted by the Smallpoxers of the uselessness and harmfulness of cowpox must have been exactly and painfully true, though persistently and ferociously denied. In the _Edinburgh Review_ for October, 1806, appeared an article entitled “Pamphlets on Vaccine Inoculation,” which may be taken as a reflection of the state of the controversy at that date, and as an index to the chief offenders against propriety. The article was written by the editor, Francis Jeffrey, and was a product of that perspicuous intelligence, which reduced to order whatever was subjected to its action, in much the same way that a housemaid “sets to rights” a library by ranging the books according to their sizes and bindings, and assorting the papers so that they lie neatly disposed. As is the habit of able editors, a view of the variolous controversy was evolved that might be comfortably accepted and confidently repeated by his readers--the evolution of such rational mirage being regarded for the time as veracious matter-of-fact. First we may take the reviewer’s evidence as to the extent and fury of the controversy--