Slightly later come Donatello's great pupils, Desiderio da Settignano (1428-1464), Andrea Verrocchio (1435-1488), and Antonio Pollaiuolo (1429-1498). The two latter are almost equally famous as painters. Contemporaneous with them are Mino da Fiesole, Bernardo and Antonio Rossellino, Giuliano da San Gallo, Giuliano and Benedetto da Maiano, of whom the last-named was the first architect of the Strozzi Palace. The last great architect of the Quattrocento is Simone del Pollaiuolo, known as Cronaca (1457-1508); and its last great sculptor is Andrea della Robbia, Luca's nephew, who was born in 1435, and lived on until 1525. Andrea's best works--and they are very numerous indeed, in the same enamelled terra-cotta--hardly yield in charm and fascination to those of Luca himself; in some of them, devotional art seems to reach its last perfection in sculpture. Giovanni, Andrea's son, and others of the family carried on the tradition--with cruder colours and less delicate feeling. Masaccio (1401-1428), one of "the inheritors of unfulfilled renown," is the first great painter of the Renaissance, and bears much the same relation to the fifteenth as Giotto to the fourteenth century. Vasari's statement that Masaccio's master, Masolino, was Ghiberti's assistant appears to be incorrect; but it illustrates the dependence of the painting of this epoch upon sculpture. Masaccio's frescoes in the Carmine, which became the school of all Italian painting, were entirely executed before the Medicean regime. The Dominican, Fra Angelico da Fiesole (1387-1455), seems in his San Marco frescoes to bring the denizens of the Empyrean, of which the mediæval mystics dreamed, down to earth to dwell among the black and white robed children of St Dominic. The Carmelite, Fra Lippo Lippi (1406-1469), the favourite of Cosimo, inferior to the angelical painter in spiritual insight, had a keener eye for the beauty of the external world and a surer touch upon reality. His buoyant humour and excellent colouring make "the glad monk's gift" one of the most acceptable that the Quattrocento has to offer us. Andrea del Castagno (died in 1457) and Domenico Veneziano (died in 1461), together with Paolo Uccello (died in 1475), were all absorbed in scientific researches with an eye to the extension of the resources of their art; but the two former found time to paint a few masterpieces in their kind--especially a Cenacolo by Andrea in Santa Appollonia, which is the grandest representation of its sublime theme, until the time that Leonardo da Vinci painted on the walls of the Dominican convent at Milan. Problems of the anatomical construction of the human frame and the rendering of movement occupied Antonio Pollaiuolo (1429-1498) and Andrea Verrocchio (1435-1488); their work was taken up and completed a little later by two greater men, Luca Signorelli of Cortona and Leonardo da Vinci.