In the British Museum there is a MS. of some importance (Sloane MS., 349), entitled 'Loimographia, an account of the Great Plague of London in the year 1665, by William Boghurst, apothecary.' This was first referred to by Mr. E. W. Brayley in his edition of Defoe's _Plague Year_, and it was analysed by Dr. Creighton in his work on Epidemics. Dr. Payne printed an edition of the tract in 1894. Mr. Brayley reprinted from the _Intelligencer_, July 31, 1665, the following curious advertisement:-- 'Whereas Wm. Boghurst, apothecary at the White Hart, in St. Giles' in the Fields, hath administered a long time to such as have been afflicted with the plague, to the number of 40, 50, or 60 patients a day, with wonderful success, by God's blessing upon certain excellent medicines which he hath, as a water, a lozenge, etc. Also an electuary antidote, of but 8d. the oz. price. This is to notify that the said Boghurst is willing to attend any person infected and desiring his attendance, either in city, suburbs or country, upon reasonable terms, and that the remedies above mentioned are to be had at his house or shop, at the White Hart aforesaid.' Boghurst gives a good deal of information in his book regarding the signs of the disease, and its treatment; and he describes the spread of the disease in London as follows:-- 'The winds blowing westward so long together, from before Christmas until July, about seven months, was the cause the plague began first at the west end of the city, as at St. Giles', St. Martin's, Westminster. Afterwards it gradually insinuated and crept downe Holborne and the Strand, and then into the city, and at last to the east end of the suburbs, soe that it was halfe a yeare at the west end of the city before the east end and Stepney was infected, which was about the middle of July. Southwark being the south suburb, was infected almost as soon as the west end. The disease spread not altogether by contagion at first, nor began at only one place, and spread further and further as an eating spreading soare doth all over the body, but fell upon severall places of the city and suburbs like raine, even at the first at St. Giles', St. Martin's, Chancery Lane, Southwark, and some places within the city, as at Proctor's House.'