In all the skulls of the large lop-eared rabbits, the bony auditory meatus is conspicuously larger than in the wild rabbit. In a skull 4.3 inches in length, and which barely exceeded in breadth the skull of a wild rabbit (which was 3.15 inches in length), the longer diameter of the meatus was exactly twice as great. The orifice is more compressed, and its margin on the side nearest the skull stands up higher than the outer side. The whole meatus is directed more forwards. As in breeding lop-eared rabbits the length of the ears, and their consequent lopping and lying flat on the face, are the chief points of excellence, there can hardly be a doubt that the great change in the size, form, and direction of the bony meatus, relatively to this same part in the wild rabbit, is due to the continued selection of individuals having larger and larger ears. The influence of the external ear on the bony meatus is well shown in the skulls (I have examined three) of half-lops (see figure 5), in which one ear stands upright, and the other and longer ear hangs down; for in these skulls there was a plain difference in the form and direction of the bony meatus on the two sides. But it is a much more interesting fact, that the changed direction and increased size of the bony meatus have slightly affected on the same side the structure of the whole skull. I here give a drawing (figure 11) of the skull of a half-lop; and it may be observed that the suture between the parietal and frontal bones does not run strictly at right angles to the longitudinal axis of the skull; the left frontal bone projects beyond the right one; both the posterior and anterior margins of the left zygomatic arch on the side of the lopping ear stand a little in advance of the corresponding bones on the opposite side. Even the lower jaw is affected, and the condyles are not quite symmetrical, that on the left standing a little in advance of that on the right. This seems to me a remarkable case of correlation of growth. Who would have surmised that by keeping an animal during many generations under confinement, and so leading to the disuse of the muscles of the ears, and by continually selecting individuals with the longest and largest ears, he would thus indirectly have affected almost every suture in the skull and the form of the lower jaw!