The Vivisectors' Directory: Being a list of the licensed vivisectors in the United Kingdom, together with the leading physiologists in foreign laboratories
Science
The Vivisectors' Directory: Being a list of the licensed vivisectors in the United Kingdom, together with the leading physiologists in foreign laboratories
Vivisection
is surrounded by warm olive oil, which, however, is not in immediate
contact with its surface, but is separated from it by a delicate flexible
membrane of a kind which has already been referred to by the author in
several of his published papers, and which prevents any escape of the oil
by the side of the blood-vessels and other structures entering the hilus
of the gland.… When the instrument is in use, the kidney lies between
two delicate, exceedingly flexible membranes, which apply themselves
closely to its surface and to the surface of the structures entering the
hilus of the organ, and each of these membranes forms with each of the
symmetrical halves of the box a chamber which is filled with oil and
which communicates by a relatively wide flexible tube with the recording
instrument.”
Experiment “4. After the immediate effect of the operation has passed
off, the volume of the kidney will usually remain unchanged (with
exception of the changes due to the pulse and respiration) for many hours
unless some change in the conditions of the experiment be intentionally
introduced.
“5. When the _Traube-Hering_ curves of the blood-pressure present
themselves, the volume of the kidney does not expand with the rhythmic
rise in the blood-pressure. With each rise of the blood-pressure the
kidney _contracts_, expanding with each fall of the blood-pressure. The
renal vessels are, therefore, amongst those to the rhythmic contraction
and expansion of which the _Traube-Hering_ waves are due.
“6. Arrest for 3 or 4 minutes of the artificial respiration, where that
is employed, and where curare has been previously injected, causes a
contraction of the renal vessels (which may reach 12 per cent of the
post-mortem volume of the kidney) simultaneously with the rise of aortic
blood pressure which is produced by the asphyxia.
“7. Stimulation of the medulla oblongata by weak induced currents causes
a powerful contraction of the renal vessels.
“8. Stimulation of the central end of a sensory nerve, _e.g._, sciatic,
brachial plexus, splanchnic, &c., causes a contraction of the renal
vessels simultaneous with the rise in the aortic blood-pressure.
Stimulation of the central end of the vagus causes a contraction of the
kidney (where the vagus of the other side has been cut to eliminate
reflex inhibition of the heart), and the renal vessels _contract_ whether
the stimulation of the central end of the vagus cause a rise or a fall of
the aortic blood-pressure.
“9. Stimulation of nearly all the roots of the splanchnic in the thorax,
and of both larger and smaller splanchnic nerve-trunks causes contraction
of the kidney of the _opposite_ side. The extent to which the kidney
contracts on stimulation of the splanchnic is usually very considerable.
In one case the kidney contracted on stimulating with a strong induced
current for three minutes to an extent which was equal to 63 per cent. of
the post-mortem volume of the organ.
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