In 1621 hostilities were renewed between Spain and the Netherlands, but even during the nominal truce the Dutch invaded Margarita, and demolished the fort, but without, however, taking actual possession. When the truce was over hostilities were recommenced with a vigour that rather astonished Spain, for in the interval the Netherlands had progressed wonderfully. In 1625, the year of his accession, Charles the First entered into a treaty, offensive and defensive, with the United Provinces, which of course brought England into collision with Spain, and open war began again in the West Indies. In 1629 a fleet of thirty-five vessels under Don Frederic de Toledo conquered the island of St. Christopher's and removed most of the English settlers, only a few of whom managed to escape to the mountains, while the French got off in two of their vessels. The French refugees suffered a great deal from the want of preparation for their hurried flight, and arrived at the island of St. Martin's perishing with hunger and thirst. Here they dug holes in the sand and obtained a supply of brackish water, which was so unwholesome that some died from drinking it in excessive quantities. After the Spaniards left they returned to St. Christopher's to find a few English, who, annoyed at their desertion, wanted to keep the island to themselves, but the French were too numerous and soon took possession of their old quarters. In 1632 the Dutch took possession of Tobago, and two years later of Curaçao, which latter island soon became their great stronghold in the West Indies, and the principal depôt for the contraband traffic with Venezuela. At that time no Spanish vessels went to this part of the Main, but finding that the trade was of some importance to the Dutch, the authorities now granted licenses to drive their rivals out of the market. But the Spanish traders could not compete with the Hollanders, and this so annoyed the authorities that they determined to extinguish smuggling at any cost. This they were unable to do by catching the delinquents, but they could punish those who dealt with them. The result was the infliction of heavy fines and confiscation, with disgraceful punishments, from which many were ruined. Yet with all that the trade was so lucrative to both parties that neither was inclined to give it up--the Dutch took care of themselves, while cheap commodities could generally command a market, whatever the risk. The fact was the mother country imposed so many restrictions, and exacted such heavy fees for licenses, that the cost of an article was doubled or trebled as compared with that of the Hollander.