So he arose from Grandfather’s chair and went out of the library. Near the door he met his son Samuel, who seemed downcast and out of spirits. The boy had heard, probably, that some of his playmates were taken ill with the small-pox. But, as his father looked cheerfully at him, Samuel took courage, trusting that either the wisdom of so learned a minister would find some remedy for the danger, or else that his prayers would secure protection from on high. Meanwhile Cotton Mather took his staff and three-cornered hat and walked about the streets, calling at the houses of all the physicians in Boston. They were a very wise fraternity; and their huge wigs, and black dresses, and solemn visages made their wisdom appear even profounder than it was. One after another he acquainted them with the discovery which he had hit upon. But the grave and sagacious personages would scarcely listen to him. The oldest doctor in town contented himself with remarking that no such thing as inoculation was mentioned by Galen or Hippocrates; and it was impossible that modern physicians should be wiser than those old sages. A second held up his hands in dumb astonishment and horror at the mad-ness of what Cotton Mather proposed to do. A third told him, in pretty plain terms, that he knew not what he was talking about. A fourth requested, in the name of the whole medical fraternity, that Cotton Mather would confine his attention to people’s souls, and leave the physicians to take care of their bodies. In short, there was but a single doctor among them all who would grant the poor minister so much as a patient hearing, This was Doctor Zabdiel Boylston. He looked into the matter like a man of sense, and finding, beyond a doubt, that inoculation had rescued many from death, he resolved to try the experiment in his own family. And so he did. But when the other physicians heard of it they arose in great fury and began a war of words, written, printed, and spoken, against Cotton Mather and Doctor Boylston. To hear them talk, you would have supposed that these two harmless and benevolent men had plotted the ruin of the country. The people, also, took the alarm. Many, who thought themselves more pious than their neighbors, contended that, if Providence had ordained them to die of the small-pox, it was sinful to aim at preventing it. The strangest reports were in circulation. Some said that Doctor Boylston had contrived a method for conveying the gout, rheumatism, sick-headache, asthma, and all other diseases from one person to another, and diffusing them through the whole community. Others flatly affirmed that the evil one had got possession of Cotton Mather, and was at the bottom of the whole business.