soundest and most indispensable supports of the theory of descent. In discussing the question of the real causes of death, we confine our attention to normal or physiological death without considering the innumerable causes of accidental or pathological death, by illness, parasites, mishaps, etc. Normal death takes place in all organisms when the limit of the hereditary term of life is reached. This limit varies enormously in different classes of organisms. Many of the unicellular protophyta and protozoa live only a few hours, others several months or years; many one-year plants and lower animals live only a summer in our temperate climate, and only a few weeks or months in the arctic circle or on the snow-covered Alps. On the other hand, the larger vertebrates are not uncommonly a hundred years old, and many trees live for a thousand years. The normal span of life has been determined in all species in the course of their evolution by adaptation to special conditions, and has then been transmitted to offspring by heredity. In the latter, however, it is often subject to considerable modifications. The organism has been compared, on the modern "machine theory" of life, to an artificially constructed mechanism, or an apparatus in which the human intelligence has put together various parts for the attainment of a certain end. This comparison is inapplicable to the lowest organisms, the monera, which are devoid of such a mechanical structure. In these primitive "organisms without organs" (chromacea and bacteria) the sole cause of life is the invisible chemical structure of the plasm and the metabolism effected by this. As soon as this ceases death takes place (_cf._ chapter ix.). In the case of all other organisms the comparison is useful in so far as the orderly co-operation of the various organs or parts accomplishes a certain task by the conversion of virtual into active force. But the great difference between the two is that in the case of the machine the regularity is due to the purposive and consciously acting will of man, whereas in the case of the organism it is produced by unconscious natural selection without any design. On the other hand, the two have another important feature in common in the limited span of life which is involved in their being used up. A locomotive, ship, telegraph, or piano, will last only a certain number of years. All their parts are worn out by long use, and, in spite of all repairing, become at last useless. So in the case of all organisms, the various parts are sooner or later worn out and rendered useless; this is equally true of the organella of the protist and the organs of the histon. It is true that the parts may be repaired or regenerated; but sooner or later they cease to be of service, and become the cause of death.