The central nervous system (fig. 94) is developed either before or after the detachment of the young Nemertine, according to Metschnikoff as a thickening of the epiblast. The young Nemertine is at first without an anus. The development of the Nemertine within the Pilidium is clearly identical with that of the Lineus embryo within the larval skin; the formation of an amnion in the Pilidium constituting the only important difference which can be pointed out between the modes of origin of the young Nemertine in the two types. So far as is known the forms which develop in a Pilidium, or according to the type of Desor, all belong to the division of the Nemertines without stylets in the proboscis, known as the Anopla. Development without Metamorphosis. The majority of the Nemertea, including the whole (?) of the Enopla, develop without a metamorphosis. The observations which have been made on this type are not very satisfactory, but appear to indicate that the formation of the hypoblast may take place either by invagination or by delamination. Invaginate types have been observed by Barrois (No. 192), Dieck (No. 196) and Hubrecht. Barrois' fullest observations were made on _Amphiporus lactifloreus_ (one of the Enopla), and those of Dieck on _Cephalothrix galatheæ_ (one of the Anopla). A regular segmentation is followed by a blastosphere stage with a small segmentation cavity. In Barrois' type the inner ends of the cells of the blastosphere are stated to fuse into a kind of syncytium. A small invagination takes place, and the cells which take part in it separate from the epiblast, and then fuse with the syncytium within the blastosphere. Dieck finds that in Cephalothrix the invaginated mass simply vanishes. Barrois' statements about the fusion of the syncytium derived from the epiblast cells with the invaginated cells must be regarded as very doubtful. The formation of the germinal layers takes place, according to Barrois, by the separation of the internal mass of cells into mesoblast and hypoblast. The proboscis is formed, according to this author, from the mesoblastic tissues. Dieck, on the other hand, with greater probability, states that the proboscis is formed by an invagination. In Cephalothrix a further point deserves notice, in that the whole of the primitive epiblast becomes shed. In this fact there may perhaps be recognised the last trace of a metamorphosis like that in the type of Desor. Delaminate types have been studied by Barrois (No. 192) and Hoffman (No. 198), both of whom give circumstantial accounts of their development.