These considerations indicate with fair probability that the part of the head containing the fore-brain is the equivalent of the præoral lobe of many Invertebrate forms; and the primitive position of the Vertebrate mouth on the ventral side of the head affords a distinct support for this view. It must however be admitted that this part of the head is not sharply separated in development from that behind; and, though the fore-brain is usually differentiated very early as a distinct lobe of the primitive nervous tube, yet that such differentiation is hardly more marked than in the other parts of the brain. The termination of the notochord immediately behind the fore-brain is, however, an argument in favour of the morphological distinctness of the latter structure. The evidence at our disposal appears to indicate that the posterior part of the head was not differentiated from the trunk in lower Chordata; but that, as the Chordata rose in the scale of development, more and more centralizing work became thrown on the anterior part of the nervous cord, and _pari passu_ this part became differentiated into the mid- and hind-brain. An analogy for such a differentiation is supplied in the compound suboesophageal ganglion of many Arthropods; and, as will be shewn in the chapter on the nervous system, there is strong embryological evidence that the mid- and hind-brains had primitively the same structure as the spinal cord. The head appears however to have suffered in the course of its differentiation a great concentration in its posterior part, which becomes progressively more marked, even within the limits of the surviving Vertebrata. This concentration is especially shewn in the structure of the vagus nerve, which, as first pointed out by Gegenbaur, bears evidence of having been originally composed of a great series of nerves, each supplying a visceral cleft. Rudiments of the posterior nerves still remain as the branches to the oesophagus and stomach[105]. [105] The lateral branch of the vagus nerve probably became differentiated in connection with the lateral line, which seems to have been first formed in the head, and subsequently to have extended into the trunk (_vide_ section on Lateral Line). The atrophy of the posterior visceral clefts seems to have taken place simultaneously with the concentration of the neural part of the head; but the former process did not proceed so rapidly as the latter, so that the visceral region of the head is longer in the lower Vertebrata than the neural region, and is dorsally overlapped by the anterior part of the spinal cord and the anterior muscle-plates (_vide_ fig. 47).