From 1823 onward, the chief scene of Charles Jenkin's activities was in the West Indies, where he was engaged off and on till 1844, now as a subaltern, now in a vessel of his own, hunting out pirates, "then very notorious," in the Leeward Islands, cruising after slavers, or carrying dollars and provisions for the Government. While yet a midshipman, he accompanied Mr. Cockburn to Caraccas and had a sight of Bolivar. In the brigantine _Griffon_, which he commanded in his last years in the West Indies, he carried aid to Guadeloupe after the earthquake, and twice earned the thanks of Government: once for an expedition to Nicaragua to extort, under threat of a blockade, proper apologies and a sum of money due to certain British merchants; and once during an insurrection in San Domingo, for the rescue of certain others from a perilous imprisonment and the recovery of a "chest of money" of which they had been robbed. Once, on the other hand, he earned his share of public censure. This was in 1837, when he commanded the _Romney_, lying in the inner harbour of Havannah. The _Romney_ was in no proper sense a man-of-war; she was a slave-hulk, the bonded warehouse of the Mixed Slave Commission; where negroes, captured out of slavers under Spanish colours, were detained provisionally, till the Commission should decide upon their case, and either set them free or bind them to apprenticeship. To this ship, already an eyesore to the authorities, a Cuban slave made his escape. The position was invidious: on one side were the tradition of the British flag and the state of public sentiment at home; on the other, the certainty that if the slave were kept, the _Romney_ would be ordered at once out of the harbour, and the object of the Mixed Commission compromised. Without consultation with any other officer, Captain Jenkin (then lieutenant) returned the man to shore and took the Captain-General's receipt. Lord Palmerston approved his course; but the zealots of the anti-slave trade movement (never to be named without respect) were much dissatisfied; and thirty-nine years later the matter was again canvassed in Parliament, and Lord Palmerston and Captain Jenkin defended by Admiral Erskine in a letter to the _Times_ (March 13, 1876).