That so much of the blood must remain as is appropriated to the nutrition of the tissues, is matter of necessity; for it cannot nourish unless it be assimilated and become coherent, and form substance in lieu of that which is lost; but that the whole of the blood which flows into a part should there remain, in order that so small a portion should undergo transformation, is nowise necessary; for no part uses so much blood for its nutrition as is contained in its arteries, veins, and interstices. Nor because the blood is continually coming and going is it necessary to suppose that it leaves nothing for nutriment behind it. Consequently it is by no means necessary that the whole remain in order that nutrition be effected. But our learned author, in the same book, where he affirms so much, appears almost everywhere else to assert the contrary. In that paragraph especially where he describes the circulation in the brain, he says: “And the brain by means of the circulation sends back blood to the heart, and thus refrigerates the organ.” And in the same way are all the more remote parts said to refrigerate the heart; thus in fevers, when the præcordia are scorched and burn with febrile heat, patients baring their limbs and casting off the bedclothes, seek to cool their heart; and the blood generally, tempered and cooled down, as our learned author states it to be with reference to the brain in particular, returns by the veins and refrigerates the heart. Our author, therefore, appears to insinuate a certain necessity for a circulation from every part, as well as from the brain, in opposition to what he had before said in very precise terms. But then he cautiously and ambiguously asserts, that the blood does not return from the parts composing the second and third regions, unless, as he says, it is drawn by force, and through a signal deficiency of blood in the larger vessels, &c., which is most true if these words be rightly understood; for by the larger vessels, in which the deficiency is said to cause the reflux, I think he must be held to mean the veins not the arteries; for the arteries are never emptied, save into the veins or interstices of parts, but are incessantly filled by the strokes of the heart; but in the vena cava and other returning channels, in which the blood glides rapidly on, hastening to the heart, there would speedily be a great deficiency of blood did not every part incessantly restore the blood that is incessantly poured into it. Add to this, that by the impulse of the blood which is forced with each stroke into every part of the second and third regions, that which is contained in the pores or interstices is urged into the smaller veins, from which it passes into larger vessels, its motion assisted besides by the motion and pressure of circumjacent parts; for from every containing thing compressed and constringed, contained matters are forced out. And thus it is that by