The study of the histology of the nervous system shows that in all parts of the body a splitting up into a number of small centres takes place, and that nowhere does a single central point susceptible of anatomical demonstration exist from which the operations of the body are directed. We find in the nervous systems definite little cells which serve as centres of motion, but we do not find any single ganglion cell in which alone all movement in the end originates. The most various individual motor apparatuses are connected with the most various individual motor ganglion cells. Sensations are certainly collected in definite ganglion cells. Still, among them, too, we do not find any single ganglion cell which can be in any way designated the centre of all sensation, but we again meet with a great number of very minute centres. All the operations which have their source in the nervous system, and there certainly are a very great number of them, do not allow us to recognise a unity anywhere else than in our own consciousness. An anatomical or physiological unity has at least as yet been nowhere demonstrated. When we talk of life we mean vital activity. Now, every vital action supposes an excitation or irritation. The irritability of the part is the criterion by which we judge whether it be alive or not. Our notion of the death of a part is based upon nothing more or less than this--that we can no longer detect any irritability in it. If we now proceed with our analysis of what is to be included in the notion of excitability, we at once discover, that the different actions which can be provoked by the influence of any external agency are essentially of three kinds. The result of an excitation or irritation may, according to circumstances, be either a merely functional process, or a more or less increased nutrition of the part, _or_ a formative process giving rise to a greater or less number of new elements. These differences manifest themselves more or less distinctly according as the particular tissues are more or less capable of responding to the one or other kinds of excitation. It certainly cannot be denied that the processes may not be distinctly defined, and that between the nutritive and formative processes, and also between the functional and nutritive ones there are transitional stages; still, when they are typically performed, there is a very marked difference between them, and considerable differences in the internal changes undergone by the excited parts.