Nor is inflammatory exudation the essential feature of inflammation. I am of the opinion that there is no specific inflammatory exudation at all, but that the exudation we meet with is composed essentially of the material which has been generated in the inflamed part itself, through the change in its condition, and of the transuded fluid derived from the vessels. If, therefore, a part possess a great number of vessels, and particularly if they are superficial, it will be able to furnish an exudation, since the fluid which transudes from the blood conveys the special product of the tissue along with it to the surface. If this is not the case, there will be no exudation, but the whole process will be limited to the occurrence in the real substance of the tissue of the special changes which have been induced by the inflammatory stimulus. In this manner, two forms of inflammation can be distinguished, the _purely parenchymatous inflammation_, where the process runs its course in the interior of the tissue, without our being able to detect the presence of any free fluid which has escaped from the blood; and the secretory (exudative) inflammation, where an increased escape of fluid takes place from the blood, and conveys the peculiar parenchymatous matters along with it to the surface of the organs. That there are two kinds of inflammation is shown by the fact that they occur for the most part in different organs. Every parenchymatous inflammation tends to alter the histological and functional character of an organ. Every inflammation with free exudation generally affords a certain relief to the parts by conveying away from it a great part of the noxious matters with which it is clogged. _New Formations_ I at present entirely reject the blastema doctrine in its original form, and in its place I put the _doctrine of the continuous development of tissues out of one another_. My first doubts of the blastema doctrine date from my researches on tubercle. I found the tubercles never exhibited a discernible exudation; but always organised elements unpreceded by amorphous matter. I also found that the discharge from scrofulous glands and from inflamed lymphatic glands is not an exudation capable of organisation but merely debris, developed from the ordinary cells of the glands.