About 1490 B.C. Thutmose III. pushed into Asia and roused the western portion of that continent with his conquests. Assyria, like many other weak states, hastened to send gifts to the conquering pharaoh. These signified submission, and Thothmes gave no further evidences of his military power. The next mention of Assyria occurs when the state had become sufficiently important to enter into a treaty with the Kassite king of Babylonia, regarding disputed territories. As we have already noted, Assyria, long subservient to the older kingdom, felt in no way bound to submit to the foreign rule of Kassite princes, and had already established her own independence, which was acknowledged by the Babylonian king when he negotiated a treaty with her. Later, the daughter of an Assyrian king was married to the king of Babylonia. Their son came to the throne at an early age, and the Babylonians, seeing an intrigue to allow Assyrian influences to dominate their land, made way with the boy-king, substituting another in his place. Thereupon the Assyrian ruler, grandfather of the murdered prince, invaded Babylonia, killed the monarch popularly crowned, and placed his own candidate upon the throne. The result of this Assyrian interference was not immediately important, but it was the first of a long series of difficulties between the two countries, which ended ultimately in the recognition of the Assyrian king as ruler of Babylonia as well. About 1290 B.C., troubles having again arisen, the northern king came once more to the city of Babylon, this time carrying away the statue of the god Marduk, as we have already seen. He left Assyrian officials in the land as his representatives. Seven years later, these were driven out by a popular uprising of the Babylonians, who seized certain outlying districts which had recently been appropriated by the Assyrians. When the Kassite princes were finally dethroned, Nebuchadnezzar I., of the dynasty of Isin, was strong enough to hold the Babylonian state intact against the power which constantly threatened at the north. To this point we had come in the preceding chapter, and this recast of the situation is made that we may have its essential features clearly in mind.