In 1835 Mr. Job R. Tyson bought Dr. Caspar Wistar’s old house, at Fourth and Prune Streets, when once more it opened its doors to the learned and jovial brotherhood. In 1840 the number of citizens who could be invited was raised to forty, while in the years succeeding the organization of the club many guests from over the sea, and from the different States of the Union, had been welcomed to the Wistar Parties. One of the latter writes,-- “During my stay in Philadelphia I was present at several of these Wistar meetings, and always returned from them with increased conviction of their beneficial tendency. “These meetings are held by rotation at the houses of the different members. The conversation is generally literary or scientific, and, as the party is usually very large, it can be varied at pleasure. Philosophers eat like other men, and the precaution of an excellent supper is by no means found to be superfluous. It acts, too, as a gentle emollient on the acrimony of debate. No man can say a harsh thing with his mouth full of turkey, and disputants forget their differences in unity of enjoyment.” Better known abroad in the early part of the century than any other American city, all travellers of consequence came to Philadelphia. Among these we find such men as General Moreau, counted after Bonaparte the greatest general in the French Republic; the younger Murat, who married Miss Fraser, of South Carolina; the Marquis de Grouchy, whose name will be forever associated with the defeat of Waterloo; the poet Moore, whose singing drew tears from the beautiful eyes of Mrs. Joseph Hopkinson; the Prince de Canino, son-in-law of Joseph Bonaparte, ex-king of Spain, who, himself residing at Bordentown until 1830, was doubtless a guest of the Wistar Association, although, after the fashion of princes, it was his pleasure to entertain rather than to be entertained. These and many more, including President Madison, and the witty and able Virginia gentleman William Short, who, as secretary of legation under Thomas Jefferson, chargé-d’affaires to the French Republic, and minister to Spain and the Netherlands, had seen much of foreign official and social life. An acquaintance of Talleyrand, himself a diplomatist, life abroad offered Mr. Short many attractions, which a friend and contemporary assures us were more than balanced by the terrors of the sea, which menaced him in the form of sea-sickness. This gentleman, a surviving member of the Wistar Association of 1837, recalls no social intercourse in Old-World cities more delightful than that of this informal club. While on a visit to Philadelphia in 1825, the Duke of Saxe-Weimar makes the following entry in his journal: