In 1842, Mr. Tyson records only two of the original members of 1818 still surviving, Dr. R. M. Patterson and Robert Walsh. The kindly face of Mr. Vaughan (Johnny Vaughan, as his intimates called him), first Dean of the Wistar Association, had only lately disappeared from the circle. Although death had sadly thinned the ranks of original membership, a number of honored names filled the blanks: among these, Horace Binney, William M. Meredith, John Sergeant, Joshua Francis Fisher, Judge Kane, Langdon Cheves, from South Carolina, Thomas Isaac Wharton, and, there always being a large proportion of medical men, such distinguished sons of the healing art as Dr. Robert Hare, Dr. Thomas C. James, Dr. John K. Mitchell, Dr. Isaac Hays, physician and writer, Dr. Franklin Bache and his friend Dr. George B. Wood closely associated with him in medical literature, Dr. Charles D. Meigs, and Moncure Robinson, Esq., who, among the many who have come and gone, still [1887] recalls delightful evenings spent at the Wistar Parties. Dr. Isaac Lea was in 1843 Dean of the association, which office he held until the stirring events of ’60 and ’61 scattered its members, not again to unite until 1886, within a few months of his death, when he was succeeded in this office by his son, Mr. Henry C. Lea.[29] Writing during this hiatus of many years, Dr. George B. Wood says,-- “I have always regarded the Wistar Club not merely as an ornamental feature of Philadelphia society, but as a very useful institution; bringing as it did persons together of various pursuits, who would not otherwise perhaps have met, thus removing prejudices and conciliating friendly feeling; and, by a regulation regarding strangers which gave each member the right to introduce one or more to the meetings, facilitating their intercourse with citizens, and contributing to the reputation of our city for hospitality.”