This church, which heretofore held the first rank in regard to its influence, being now composed entirely of Gentiles, and stripped of its apostolic character and influence, could no longer successfully oppose the growing ambition and influence of the bishops of the church in the metropolis of the empire. Up to this period, and for some time after, there does not appear to have been any change in the sentiments or practice of the church, in any place, relative to the Sabbath; but from what is related by subsequent writers, which will be noticed in its place, it is certain that it was observed by the churches universally. This fact is so generally acknowledged by those acquainted with the history of the matter, that we need refer to only a few passages in proof. The learned _Grotius_ says, in his Explication of the Decalogue, "Therefore the Christians also, who believed Christ would restore all things to their primitive practice, as Tertullian teacheth in _Monogamia_, kept holy the Sabbath, and had their assemblies on that day, in which the law was read to them, as appears in Acts 15:21, which custom remained till the time of the council of Laodicea, about A. D. 365, who then thought meet that the gospels also should be read on that day." _Edward Brerewood_, Professor in Gresham College, London, in a Treatise on the Sabbath, 1630, says: "It is commonly believed that the Jewish Sabbath was changed into the Lord's day by Christian emperors, and they know little who do not know, that _the ancient Sabbath did remain and was observed by the eastern churches three hundred years after our Saviour's passion_."