Treatise on Poisons: In relation to medical jurisprudence, physiology, and the practice of physicChristison, Robert, Sir
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Treatise on Poisons: In relation to medical jurisprudence, physiology, and the practice of physic
Christison, Robert, Sir
Medical jurisprudence; Toxicology
Although morbid and pseudo-morbid redness of the inner coat of the
alimentary canal cannot be distinguished from one another by any
intrinsic character, M. Billard thinks this may be done by attending to
collateral circumstances. According to his researches, redness is to be
accounted inflammatory only when it occurs in parts not depending in
position, or is not limited to such parts: when the mesenteric veins
supplying the parts are not distended, nor the great abdominal veins
obstructed at the time of death; when the reddened membrane is covered
with much mucus, particularly if thick, tenacious, and adhering; when
the mucous membrane itself is opaque, so that when dissected off and
stretched over the finger, the finger is not visible; when the cellular
tissue which connects that membrane with the subjacent coat is brittle,
so that the former is easily scratched off with the nail.
Some observations may be here also made on another appearance, allied to
the present group, but which there is strong reason to believe always
indicates some violent irritation at least, if not even irritation from
poison only, in the organ where it is found. It is an effusion under the
villous coat of the stomach, and incorporation with its substance, of
dark brownish-black, or as it were charred, blood; which is thus altered
either by the chemical action of the poison, or by a vital process. In
many cases of poisoning with the mineral acids, oxalic acid, arsenic,
corrosive sublimate, and the like, there are found on the villous coat
of the stomach little knots and larger irregular patches and streaks,
not of a reddish-brown, reddish-black, or violaceous hue, like
pseudo-morbid redness, but dark-grayish-black, or brownish-black, like
the colour of coal or melanosis,—accompanied too with elevation of the
membrane, frequently with abrasion on the middle of the patches, and
surrounded by vascularity. This conjunction of appearances I have never
seen in the stomach, unless it had been violently irritated; and several
experienced pathologists of my acquaintance agree with me in this
statement. It bears a pretty close resemblance to melanosis of the
stomach;[199] but is distinguished by melanotic blackness being arranged
in regular abruptly-defined spots, and still better by melanosis not
being preceded by symptoms of irritation in the stomach.
Referring to what was already said under the head of the symptoms of
gastritis [p. 102], I must again express my doubts whether the
appearances now described ever arise in this country from natural
disease. In the intestines they are sufficiently familiar to the
physician, as arising from idiopathic enteritis, and from dysentery. But
in the stomach their existence as the effect of natural disease is very
doubtful.
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