Treatise on Poisons: In relation to medical jurisprudence, physiology, and the practice of physicChristison, Robert, Sir
Science
Treatise on Poisons: In relation to medical jurisprudence, physiology, and the practice of physic
Christison, Robert, Sir
Medical jurisprudence; Toxicology
3. _When in a state of compound mixture_, nitric acid, like sulphuric
acid in similar circumstances, may be after a time partly decomposed and
partly neutralized; and when the matter with which it is mixed belongs
to either of the organic kingdoms, more particularly to the animal
world, its decomposition is more rapid than that of sulphuric acid.
Still it is an important fact, that some of the acid may be discovered
after a considerable interval. M. Ollivier detected it in various stains
on the skin at least a day after it had been applied;[308] Dr.
O’Shaughnessey detected it in a stain on cloth sent to him from Ireland
to Edinburgh;[309] and I have found it in stains made on broad-cloth
with detached drops seven weeks before.
_Process for Stains._ Nitric acid produces on the skin a yellow stain,
which gradually becomes dirty orange, and finally of a dirty
yellowish-brown; but in all of these states it is at once rendered for a
time lively yellow by the action of ammonia. I am not aware that any
other yellow stain is similarly affected. Stains on cloth are generally
yellow, reddish-yellow, or brownish-yellow, and are attended with more
or less disintegration of the texture of the cloth. The method of
analyzing all these stains is as follows:—The stained parts is to be
boiled in a few drachms of pure water several times in succession; and
the liquid is then filtered, and may be subjected to litmus-paper for
the purpose of ascertaining its acidity. It is then to be rendered
neutral, or for the sake of greater facility, feebly alkaline, by adding
a few drops of a diluted solution of caustic potass, after which the
whole is evaporated to dryness, and in a vapour-bath, if practicable.
The residuum is then to be decomposed by sulphuric acid in the same way
as recommended above for the simple diluted acid.—Orfila thinks it
advantageous to let the stains macerate for some hours in a solution of
bicarbonate of soda rather than to boil them in water. In that case,
however, it is necessary to ascertain the acidity of the stains with
litmus-paper before proceeding to macerate them.
_Process for Mixtures._ The detection of nitric acid in compound
mixtures, such as the contents of the stomach, is not so easy a matter
as its detection in stains; and indeed a sure and delicate process is
still a desideratum in medico-legal chemistry. The process varies, as in
the case of sulphuric acid, according as the subject of analysis is acid
or neutral.
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