Treatise on Poisons: In relation to medical jurisprudence, physiology, and the practice of physicChristison, Robert, Sir
Science
Treatise on Poisons: In relation to medical jurisprudence, physiology, and the practice of physic
Christison, Robert, Sir
Medical jurisprudence; Toxicology
have hitherto found recorded death took place in forty hours, and the
symptoms were violent pain in the stomach and continual vomiting,
together with the discharge by clysters of small fragments of
phosphorus, which were discovered by their shining in the dark, and
subsequently by the appearance of burnt spots on the bed-linen. In this
case, which is described by Dr. Flachsland of Carlsruhe,[326] the
quantity of the poison taken was not ascertained. The patient, a young
man, took it on bread and butter at the recommendation of a quack, to
cure constipation, general debility, and impotence.
At one time it was the custom to give small doses of phosphorus in
medical practice; but the uncertainty and occasional severity of its
operation have perhaps properly expelled it from most modern
pharmacopœias. Among other properties ascribed to it in medicinal doses,
it is said to be a powerful aphrodisiac: No such symptom occurred in the
first of the fatal cases just related, or is mentioned in any of the
others; but there is no doubt that medicinal doses sometimes produce it.
As to the morbid appearances, the same changes of structure may be
expected as in the instance of the mineral acids generally. In Worbe’s
case quoted above, the skin was generally yellow, and here and there
livid; the lungs gorged with blood; the muscular coat of the stomach
inflamed, but the other coats not, except near the two extremities of
the organ, where they were black. In Flachsland’s case much fluid blood
was discharged from the first incisions through the skin of the belly;
the omentum and outside of the stomach and intestines were red; the
villous coat of the stomach presented an appearance of gangrenous
inflammation (probably black extravasation only); the inner membrane of
the duodenum was similarly affected; the great intestines were
contracted to the size of the little finger; the mesenteric glands
enlarged; and the kidneys and spleen inflamed. In Maier’s case the
peritonæum and omentum were dry and vascular, the stomach and small
intestines pale, the great intestines contracted, almost empty,
brownish-red, and here and there inflamed, the liver large, and the
blood everywhere liquid. The contents of the caput cœcum had an odour of
phosphorus, and here were found two yellowish lumps weighing eight
grains, which shone when rubbed, exhaled a phosphoric odour, and
contained 0·6 of a grain of phosphorus. In Martin-Solon’s case the
gullet was cherry-red and its epithelian brittle, the villous coat of
the stomach grayish and brittle, the solid viscera in the abdomen soft,
and the cerebral membranes congested.
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