Orfila has omitted in his paper a serious fallacy to which this, as well as every process for the detection of acetic acid in the contents of the stomach is exposed,—namely, that the natural secretions of the stomach, according to the researches of many physiologists, but more especially in recent times those of Tiedemann and Gmelin in Germany, and those of Leuret and Lassaigne in Paris, frequently contain a small proportion of acetic acid. Hence, the inference in favour of the introduction of acetic acid into the stomach from without, founded on the process related above, is only legitimate when the quantity discovered is considerable.—The medical jurist ought also to keep in mind that vinegar is a common remedy with the vulgar for many diseases, and especially for poisoning. SECTION II.—_Of the Effects of Acetic Acid on Man and Animals._ In the first edition of this work, it was stated that acetic acid could scarcely be considered a poison. And in illustration, a case was mentioned which fell under my own notice,—that of a gentleman, who during dinner swallowed at a draught about eight ounces of vinegar by mistake for beer, and who nevertheless sustained no harm although he retained it all, and as the only measure of precaution, swallowed after it an equal quantity of port wine. In farther confirmation of what is here mentioned, it may be added, that an ounce of acid equal in strength to the pyroligneous vinegar, has been found by Schubarth of Berlin to produce very little effect when administered to a dog. The animal merely frothed a little at the mouth; cried and became restless for a time; then had one or two attacks of vomiting; and in an hour appeared quite well again.[379] Nay, it has even been found by Pommer of Heilbronn, that a considerable quantity of diluted acetic acid may be injected into the blood without causing any mischief. He injected six drachms of distilled vinegar into the femoral vein of one dog, and an ounce into the jugular vein of another, but observed no effect whatever, except a slight labour of respiration for a short time afterwards.[380]