Treatise on Poisons: In relation to medical jurisprudence, physiology, and the practice of physicChristison, Robert, Sir
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Treatise on Poisons: In relation to medical jurisprudence, physiology, and the practice of physic
Christison, Robert, Sir
Medical jurisprudence; Toxicology
Although acetic acid in its various forms is daily in the hands of every
body, one case only of poisoning with it in the human subject has
hitherto been made public. It is described by MM. Orfila and
Barruel.[384] A girl was seen in a village near Paris at eleven at night
apparently intoxicated. Five hours afterwards she was found lying on the
ground in great agony; and after complaining of pain in the stomach and
experiencing several attacks of convulsions, she expired. On the
subsequent examination of the body considerable lividity was observed on
the skin of the depending parts. The back of the tongue was brownish and
leathery, and the inner membrane of the gullet blackish-brown,
intersected by a fine network of vessels. The stomach presented
internally several large, black, firm elevations, owing to the injection
of coagulated blood into the submucous cellular tissue; and elsewhere it
had a grayish-white tint, with here and there a reddish colour; but the
mucous membrane was perfectly entire. The cavity contained above eight
ounces of a thick, blackish fluid; and a thicker pulpy matter of the
same colour adhered firmly to the villous coat. The intestines were
healthy, and so also were the other organs in the belly and chest. The
uterus contained a fœtus two months and a half old. The contents of the
stomach were subjected to a careful analysis by MM. Orfila and Barruel,
who found that they did not contain any appreciable quantity of free
sulphuric or muriatic acid, or of any of the common metallic poisons;
and by the process of analysis formerly described, they succeeded in
separating from the impure mass three drachms of a pure, and tolerably
concentrated acetic acid, besides two drachms more from the contents of
the intestines. As the residue of the distillation left behind in the
retort did not yield any bitter principle to boiling alcohol, so as to
countenance the idea of a vegetable alkaloid having been given along
with the acetic acid, they inferred that this acid had been swallowed
alone; and the experiments of Orfila on dogs, performed for the
occasion, induced them to conclude that it was the cause of death.
To these observations it is only farther necessary to add, that the
concentrated acid is a powerful irritant and even corrosive when applied
externally; which properties are owing to its power of dissolving many
of the soft animal solids.[385]
CHAPTER VI.
OF POISONING WITH OXALIC ACID.
The last poison of this order is oxalic acid. It is a substance of very
great interest; for it is a poison of great energy, and in this country
is in common use for committing suicide, and has been often taken by
accident for Epsom salt.
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