Treatise on Poisons: In relation to medical jurisprudence, physiology, and the practice of physicChristison, Robert, Sir
Science
Treatise on Poisons: In relation to medical jurisprudence, physiology, and the practice of physic
Christison, Robert, Sir
Medical jurisprudence; Toxicology
It is the most rapid and unerring of all the common poisons. The London
Courier contains an inquest on the body of a young man who appears to
have survived hardly ten minutes;[405] an equally rapid case of a young
lady, who poisoned herself with an ounce, is mentioned in the St.
James’s Chronicle;[406] and few of those who have died survived above an
hour. This rule, however, is by no means without exception. Mr. Hebb has
described a case which did not prove fatal for thirteen hours;[407] Dr.
Arrowsmith of Coventry has favoured me with the particulars of a very
interesting case which lasted for the same period: and Mr. Frazer has
accurately described another, in which, after the patient seemed to be
doing tolerably well, an exhausting fever, with dyspepsia and singultus,
carried him off in twenty-three days.[408]
Among the fatal cases the smallest dose has been half an ounce; but
there can be little doubt that less would be sufficient to cause death.
Dr. Babington of Coleraine has published a case where very severe
effects were produced by only two scruples.[409]
Very few persons have recovered where the quantity was considerable.
In every instance in which the dose was considerable, and the solution
concentrated, the first symptoms have been immediate burning pain in the
stomach, and generally also in the throat. But when the dose was small,
more particularly if the solution was also rather diluted, the pain has
sometimes been slight, or slow in commencing. Mr. Hebb’s patient, who
took only half an ounce dissolved in ten parts of water, and diluted it
immediately after with copious draughts of water, had not any pain in
the belly for six hours.
In general, violent vomiting follows the accession of pain, either
immediately, or in a few minutes; and it commonly continues till near
death. Some, however, have not vomited at all, even when the acid was
strong and in a large dose; and this is still more apt to happen when
the poison has been taken much diluted. The man last mentioned did not
vomit at all for seven hours, except when emetics were administered. The
vomited matter, as in this man’s case, and in that of Mr. Frazer’s
patient, is sometimes bloody. Instant discharge of the poison by
vomiting does not always save the patient’s life: A woman who swallowed
two ounces died in twenty minutes, although she vomited almost
immediately after taking the poison.[410]
The tongue and mouth occasionally become inflamed if the case lasts long
enough. In an instance of recovery, which happened not long ago in St.
Thomas’s Hospital, London, the tongue was red, swollen, tense and
tender, the day after the acid was swallowed.[411]
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