Treatise on Poisons: In relation to medical jurisprudence, physiology, and the practice of physicChristison, Robert, Sir
Science
Treatise on Poisons: In relation to medical jurisprudence, physiology, and the practice of physic
Christison, Robert, Sir
Medical jurisprudence; Toxicology
Another form perhaps equally common with that just described, and not
less certainly fatal, commences like the rest with violent symptoms of
irritation in the mouth, gullet, and stomach; but the bowels are not
affected, and by and by it becomes apparent that the stomach is little
injured; dysphagia or even complete inability to swallow, burning pain
and constriction in the gullet, hawking and coughing of tough, leathery
flakes, are then the leading symptoms; at length the case becomes one of
stricture of the œsophagus with or without ulceration; the bougie gives
only temporary relief, and the patient eventually expires either of mere
starvation, or of that combined with an exhausting fever. Mr. Dewar has
related a very striking example of this form of poisoning with the
alkalis.[442] His patient, after the first violent symptoms had
exhausted themselves, which took place in sixteen or eighteen hours,
suffered little for four or five days till the sloughs began to separate
from the lining membrane of the mouth, throat, and gullet. The affection
of the gullet then became gradually predominant, and terminated in
stricture, of which she appears to have been several times so much
relieved as to have been thought in a fair way of recovery. After
repeatedly disappointing Mr. Dewar’s hopes of a successful issue by her
intemperance in the use of spirituous liquors, she died of starvation
about four months after swallowing the poison. Sir Charles Bell has
noticed three parallel cases, and has given delineations of the
appearance in the gullet of two of them.[443] One of his patients did
not die till twenty years after swallowing the poison, which in this
instance was soap-less; yet he does not hesitate to ascribe the
stricture to that cause, and says death arose purely from starvation.
The carbonate of soda, though a salt in very common use, has not
hitherto been the cause of accident, which has found its way into print.
It is plainly much less actively corrosive than carbonate of potass, and
is therefore probably in every sense less energetic.
SECTION III.—_Of the Morbid Appearances caused by the fixed Alkalis._
The morbid appearances caused by potass, soda, and their carbonates
differ with the nature of the case.
In the boy who died in twelve hours Mr. Dewar found the inner membrane
of the throat and gullet almost entirely disorganized and reduced to a
pulp, with blood extravasated between it and the muscular coat. The
inner coat of the stomach was red, in two round patches destroyed, and
the patches covered with a clot of blood;—its outer coat, as well as all
the other abdominal viscera, was sound.
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