Treatise on Poisons: In relation to medical jurisprudence, physiology, and the practice of physicChristison, Robert, Sir
Science
Treatise on Poisons: In relation to medical jurisprudence, physiology, and the practice of physic
Christison, Robert, Sir
Medical jurisprudence; Toxicology
Its solubility is impaired by the presence of organic principles. When
mixed with mucus or milk it dissolves, according to Hahnemann, with
great difficulty; and I have found that a cup of tea, left beside the
fire at a temperature of 200° for half an hour upon two grains of the
oxide, does not take up entirely even that small quantity. An important
consequence of the fact now mentioned is, that when swallowed in the
solid state, little or no arsenic may be found in the fluid contents of
the stomach. In a case which occurred to Scheele three grains of solid
arsenic were found in the contents, but hardly a trace in solution.[505]
It would be wrong, however, to suppose that it is never found in the
fluid contents. For, not to mention the observations of others, I have
myself often detected it in the fluid part of the stomach in persons
poisoned by arsenic.
The solution of oxide of arsenic in boiling water yields minute crystals
on cooling, which, when their form is defined, are octaedres. In this
state, on account of its whiteness and brilliancy, it exceedingly
resembles pounded sugar. By spontaneous evaporation I have procured in
twelve months fine octaedres nearly as large as peas. These do not
become opaque by keeping, like the sublimed masses.
A difference of opinion prevails as to the action of the oxide on
vegetable colours. This is a matter of no great consequence to the
medical jurist; but it is right not to leave a disputed point without
some notice. Guibourt says the transparent variety faintly reddens
litmus, while the opaque variety faintly restores to blue litmus
previously reddened.[506] My own experiments are at variance with these
statements: I have always found that the solution of the powder, which
is of the opaque variety, faintly reddens litmus, and does not alter
reddened litmus.
The remaining chemical properties of the oxide, which it is necessary
for the medical jurist to know, will be mentioned under what is now to
be said of the principal test by which its presence may be ascertained.
Under this head will be noticed, first the tests for the solid oxide,
secondly, those for its solution, and lastly, the method of detecting it
when mingled with vegetable or animal solids and fluids, such as the
contents and tissues of the stomach.
_Of the Tests for Arsenic in the solid state._
The most characteristic and simple test for oxide of arsenic in its
solid state, either pure or mixed or combined with inorganic substances,
is its reduction to the metallic state.
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