Treatise on Poisons: In relation to medical jurisprudence, physiology, and the practice of physicChristison, Robert, Sir
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Treatise on Poisons: In relation to medical jurisprudence, physiology, and the practice of physic
Christison, Robert, Sir
Medical jurisprudence; Toxicology
These are the alkaline arsenites and arseniates, arsenic acid, arsenious
acid, the black oxide or fly-powder, and arseniuretted-hydrogen. With
regard to arsenic acid, and the alkaline arseniates and arsenites, it is
probable, from their effects in medicinal doses, that they are as active
as the white oxide, if not more so. But they have not been particularly
examined, as they are not objects of great interest to the medical
jurist.
The fly-powder or black oxide is very active. Renault found that four
grains killed a middle-sized dog in ten hours.[583] It has been likewise
known to prove quickly fatal to man. In a French journal there is a case
related which ended fatally in sixteen hours;[584] and in the Acta
Germanica is an account of four persons, who died in consequence of
eating a dish of stewed pears poisoned with it, and of whom three died
within eighteen hours.[585] The dose is not mentioned; but it is
probable from the collateral circumstances that it was not considerable.
Arseniuretted-hydrogen is probably the most active of all arsenical
compounds. The celebrated German chemist Gehlen, having accidentally
inhaled a small portion of it, died in nine days with the usual symptoms
of arsenical poisoning. In Dr. O’Reilly’s case, which proved fatal in
seven days, it was computed that the equivalent of twelve grains of
oxide had been inhaled. And Dr. Schlinder’s patient had inhaled a
quantity of gas corresponding with only an eighth of a grain of
sesquioxide; yet he appears to have made a narrow escape.[586]
It is of some consequence to settle with precision the power of the
white oxide. Witnesses are often asked on trials how small a quantity
will occasion death? It is obvious that this question admits only of a
vague answer: It can be answered at all only in reference to concomitant
circumstances, and even then but presumptively. Nevertheless, it is
right to be aware what facts are known on the subject.
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