Delirium sometimes accompanies the advanced stage, and stupor also is not unfrequent. Coma occasionally precedes death, as in Mr. Stallard’s case (p. 235), in which the symptoms of irritation, at first very violent, gradually gave place in two hours to complete insensibility, proving fatal in two hours more. Very often, however, the patient remains quite sensible to the last. Death in general comes on calmly, but is sometimes preceded by a paroxysm of convulsions.[622] In some cases it takes place quite unexpectedly, as if from sudden deliquium, as in a case mentioned by Dr. Dymock of this city. The patient, a girl who had taken two ounces intentionally, rose from her bed without help two hours and a half afterwards, went to a chair at the fireside, and had scarce sat down when she expired.[623] Various eruptions have at times been observed, especially in those who survive several days; but they are more frequent in the kind of cases to be considered afterwards, in which life is prolonged for a week or more. The eruptions have been variously described as resembling petechiæ, or measles, or red miliaria, or small-pox. In the case already quoted from Guilbert a copious eruption of miliary vesicles appeared on the fifth day, and for fifteen days afterwards. They were attended with perspiration and abatement of the other symptoms, and followed with desquamation of the cuticle. Another external affection which may be noticed is general swelling of the body. Several cases of this nature have been described by Dr. Schlegel of Meiningen; and in one of them the swelling, particularly round the eyes, appears to have been considerable.[624] In some cases of the kind now under consideration a short remission or even a total intermission of all the distressing symptoms has been witnessed, particularly when death is retarded till the close of the second or third day.[625] This remission, which is accompanied with dozing stupor, is most generally observed about the beginning of the second day. It is merely temporary, the symptoms speedily returning with equal or increased violence. Sometimes the remission occurs oftener than once, as in a case related in the London Medical and Physical Journal. The patient, a child seven years old, lived thirty-six hours in a state of alternate calm and excitement; and during the state of calm no pulse was to be felt at the wrists.[626]—So far as at present appears a long intermission is impossible.