Treatise on Poisons: In relation to medical jurisprudence, physiology, and the practice of physicChristison, Robert, Sir
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Treatise on Poisons: In relation to medical jurisprudence, physiology, and the practice of physic
Christison, Robert, Sir
Medical jurisprudence; Toxicology
A good example of epilepsy supervening on the ordinary symptoms of
inflammation has been minutely related by Dr. Roget. A girl swallowed a
drachm of arsenic, and was in consequence attacked violently with the
usual symptoms of irritation in the whole alimentary canal. After being
ill about twenty-four hours, she experienced several distinct remissions
and had some repose, attended with fainting. In twelve hours more she
began to improve rapidly; the pain subsided, her strength and spirits
returned, and the stomach became capable of retaining liquids. So far
this patient laboured under the common effects of arsenic. But a new
train of symptoms then gradually approached. Towards the close of the
second day she was harassed with frightful dreams, starting from sleep,
and tendency to faint; next morning with coldness along the spine,
giddiness, and intolerance of light; and on the fourth day with aching
of the extremities and tingling of the whole skin. These symptoms
continued till the close of the sixth day, when she was suddenly seized
with convulsions of the left side, foaming at the mouth, and total
insensibility. The convulsions endured two hours, the insensibility
throughout the whole night. Next evening she had another and a similar
fit. A third, but slighter fit occurred on the morning of the tenth;
another next day at noon; and they continued to return occasionally till
the nineteenth day. For some time longer she was affected with tightness
across the chest and stomach complaints; but she was eventually restored
to perfect health.[659]
A characteristic set of similar cases, which occurred in London in 1815,
has been related in a treatise on arsenic by Mr. Marshall.[660] They
were the subject of investigation on the trial of Eliza Fenning, a
maid-servant, who attempted to poison the whole of her master’s family
by mixing arsenic with a dumpling, and whose condemnation excited an
extraordinary sensation at the time, as many persons believed her to be
innocent. Five individuals partook of the poisoned dish, and they were
all violently seized with the usual inflammatory symptoms. But farther,
one had an epileptic fit on the first day, which returned on the second,
and he had besides frequent twitches of the muscles of the trunk, a
feeling of numbness in one side, and heat and tingling of the feet and
hands. Another had tremors of the right arm and leg on the first day,
and several epileptic fits in the course of the night. During the next
fifteen days he had a paroxysm every evening about the same hour; which
returned after an intermission of eight days, and frequently for several
months afterwards.
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