Treatise on Poisons: In relation to medical jurisprudence, physiology, and the practice of physicChristison, Robert, Sir
Science
Treatise on Poisons: In relation to medical jurisprudence, physiology, and the practice of physic
Christison, Robert, Sir
Medical jurisprudence; Toxicology
The present objection is generally and perhaps justly considered a
stronger one, when it is applied to other species of animals. But it
must be confessed after all, that our knowledge of the diversities in
the action of poisons on different animals is exceedingly vague, and
founded on inaccurate research; and there is much reason to suspect,
that, if the subject is studied more deeply, the greater number of the
alleged diversities will prove rather apparent than real. Both reasoning
and experiment, indeed, render it probable, that some orders, even of
the perfect animals, such as the _Ruminantia_, are much less sensible
than man to many poisons, and especially to poisons of the vegetable
kingdom. But so far as maybe inferred from the only accurate inquires on
the subject, their effects differ in degree more than in kind. Some
exceptions will without doubt be found to this statement. For example,
oxalic acid, besides inflaming the stomach, causes violent convulsions
in animals, but in man it for the most part excites merely excessive
prostration; and opium most generally excites in man pure sopor, in
animals convulsions also. Other exceptions, too, exist by reason of
functional peculiarities in certain animals. Thus irritant poisons do
not cause vomiting in rabbits or horses, because these animals cannot
vomit; neither do they appear to cause much pain to rabbits, because
rabbits have not the power of expressing pain with energy. But
exceptions like these, and particularly such as are unconnected with
functional peculiarities, will probably prove fewer in number, and less
striking than is currently imagined. For it is, on the other hand, well
ascertained, that many, indeed most of the active poisons whose effects
have been examined by a connected train of experiments, produce nearly
the same effects on all animals whatever from the highest to the lowest
in the scale of perfection. It has been fully proved, that arsenic,
copper, mercury, the mineral acids, opium, strychnia, conia, white
hellebore, hydrocyanic acid, cyanogen gas, sulphuretted hydrogen, and
many others, produce nearly the same effects on man, quadrupeds, birds,
amphibious animals, and even on fishes and insects.[106]
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