Sometimes it has been pleaded by the prisoner that he gave the poison by mistake. In all such cases, if he descends to particulars, which he cannot help doing, there is every likelihood that the falsehood of the defence will be made evident by the particulars of the story not agreeing with other particulars of the moral or medical evidence. At present it is only necessary to allude to inconsistencies in his story with the medical facts. No general rules can be laid down on the method of investigating a case with a view to evidence of this kind: I must be satisfied with an illustration from an actual occurrence. On the trial of Mr. Hodgson, a surgeon, at the Durham Autumn Assizes in 1824, for attempting to poison his wife, it was clearly proved, that pills containing corrosive sublimate, and compounded by the prisoner, were given by him to her in place of pills of calomel and opium, which had been ordered by her physician. But it was pleaded by him, that, being at the time intoxicated, he had mistaken, for the shop-bottle which contained opium, the corrosive-sublimate bottle which stood next it. This was certainly an improbable error, considering the opium was in powder, and the sublimate in crystals. But it was not the only one which he alleged he had committed. Not long after his wife took ill, the physician sent the prisoner to the shop to prepare for her a laudanum draught, with water for the menstruum. When the prisoner returned with it, the physician, in consequence of observing it to be muddy, was led to taste it, before he gave it to the sick lady: and finding it had the taste of corrosive sublimate, he preserved it, analyzed it, and discovered that it did contain that poison. The prisoner stated in defence, that he had a second time committed a mistake, and instead of water had accidentally used for the menstruum a corrosive-sublimate injection, which he had previously prepared for a sailor. This was proved to have been impossible; for the injection contained only five grains to the ounce, while the draught, which did not exceed one ounce, contained fourteen grains.[129] I believe it must be allowed, that, as the medical inquiries preparatory to trial are commonly conducted without the inspector being made acquainted with the moral circumstances in detail, it is rarely possible for him to foresee what points should be attended to, with the view of illustrating the intent. But the case now related will show that it is impossible for him to render his inquiries too minute or comprehensive; and more particularly, it shows the propriety of ascertaining, whenever it is possible, not only the nature but likewise the quantity of the poison. 5. The next article among the moral circumstances,—the simultaneous illness of other members of the family besides the person chiefly affected,—depends for its conclusiveness almost entirely upon the researches and opinion of the medical witnesses.