Gentlemen, I have detained you a long time upon this, but not, I trust, too long, if the view I have submitted be one worthy of your consideration. I infer from all this that Palmer had no interest whatever to put Cook to death; that it was contrary to his interest in a pecuniary point of view, and brought claims upon him, some of them small, others of a larger amount, of which he might have shared the liability with Cook, if not have thrown it entirely upon Cook; that it forced an immediate settlement of the affairs of Cook, not with Cook himself, who was an easy man--it is plain he was--and probably their solicitors, and that therefore in a pecuniary sense he had every motive of interest to desire that Cook should live; and further, he had no chance of getting a ready payment from these documents--but with hard and exacting executors of the £13,000, no chance of the sudden death of Cook passing without suspicion and inquiry, and therefore he could not think it safe for him that he should die. I cannot, I think, be so much mistaken as that a considerable portion of these observations is not well worthy your attention. I humbly contend that the suggested motive altogether fails; and I conclude that head of the observations which I have to address to you by saying that I submit respectfully to you, to the Court, and to my learned friends that that portion of this case has failed. It could not be the interest of Palmer that Cook should die. I now proceed to the next head, and it is impossible in dealing with this evidence to observe altogether the order of date. I must group the facts as well as I can in order to deal with the whole of the evidence. The question is whether the symptoms of Cook before his death and the appearance presented by his body after death were consistent with the theory of his having died by strychnia poison, and inconsistent with the theory of his having died from other and natural causes. It is under this head, gentlemen, that I shall discuss, I hope not at undue length, the medical evidence in this cause, and present to you such observations as occur to me upon the witnesses who have been called to support the view which the Crown takes of the effect of that medical evidence. [Sidenote: Serjeant Shee]