Out of space, positive and negative electrons constantly pass into the human body, their effect we feel at once; when, for instance, in a cold room, we commence to feel chilly, or on removal to a warm room, or into the sunlight, a comfortable feeling of warmth pervades the body and restores its normal temperature. Weather and local conditions have no small influence upon our state of health. In dry and elevated positions or in warm weather the condition of the body is more positive; in damp, low-lying places and in raw weather the electro-magnetic forces have a negative tendency. _This is the explanation of those disturbances of health which occasionally arise and which we sometimes experience in the dire form of epidemics._ As an illustration, the difference of climatic conditions between the adjoining States of Washington and Oregon are a case in point. Among other disturbing influences which effect the electro-magnetic forces of the body are _overfeeding_ and _underfeeding, too much_ and _too little exercise_, particularly too much or too little _stimulation_, or _false stimulation_, or excitement of a physical or mental nature. Any one of these influences may produce disorder in the relations of the electro-magnetic forces of the body. The positive or negative electrons may be abnormally increased or diminished or their location disturbed. When the body contains too many negative, slowly vibrating forces, or electrons, and its aggregate of electron vibration is consequently diminished, the result follows that the feeling of strength--the vitality, that is, becomes depressed; we feel weak, tired in the limbs; we possess little warmth and easily grow cold; metabolism falls below the normal; the skin becomes pale and so causes the overplus of negative electrons stored in the mucous membrane to set up a morbid action of that structure. Catarrh sets in. In short, negative diseases are the immediate result; such, for example, as nervous debility, anaemia, diabetes, catarrh of the stomach, intestines or air passages, _influenza_, cholera and diphtheria. In these conditions the principles of physiological chemistry laid down by me may well be called into service and improvement effected by a correct adjustment of diet. When there is an excess of rapidly vibrating, positive electrical forces, or electrons, raising the vitality of the nerves and blood above the normal, the sufferer becomes easily excitable; the body is hot and inclines to inflammatory, feverish or positive diseases, which take the form of inflammation of the lungs, measles, scarlet fever, chicken-pox, typhoid fever, etc.