The dissolving packs of long duration must be applied somewhat thinner than the cooling ones (from 1 to 3 folds); they must be wrung out more vigorously, and covered more closely. If a pack should be applied for the sake of prevention of disease, it may be put on in the evening and remain all night. In the beginning of fever, while it remains moderate, the patient can endure the pack for from 2 to 2-1/2 hours. Biological hygienic therapy rejects the external application of ice, for it causes severe congestion of the blood. Extensive application of the ice pouch causes more or less paralysis of the nerves, which in many cases prevents recovery and even causes chronic disease or fatal results. The biological hygienic treatment desires _to moderate inflammation only_, to the degree that it should lose its dangerous character, but it leaves to the body its power _to remove, through the process of inflammation, alien and diseased matter, and to absorb and gradually carry away the products of inflammation through the blood current_. Paralysis of the vocal cords, of the muscles of the eye, of the nerves of hearing, the exudations from the nose and eyes after diphteria, meningitis and scarlet fever, adhesions, suppurations after pneumonia and other forms of inflammatory disease, are often the _consequences of the use of ice_, because the products of inflammation are not absorbed, and the ice paralyzes the neighbouring nerves. Inflammations, which are suppressed by medicine or ice, must renew themselves; since the causes, the alien matter (auto toxins), as well as the products of inflammation remain in the body and are not thoroughly excreted. To apply water, on the contrary, quickly removes not only the inflammation, but its causes and eventual consequences. The organs which have been inflamed do not show any further inclination to renewed inflammation. In no case will a chronic ailment be the consequence of an acute disease, provided the same is dealt with in a natural way, according to the principles of biological hygienic treatment. In order to bring about the complete excretion of all autotoxins and, in case of inflammation, the complete absorption of all products thereof, it is necessary to continue the lengthy packs even during the period of convalescence, and not to stop immediately the fever and inflammation have somewhat disappeared. This is a mistake which is frequently committed, and the fault is then laid at the door of the biological hygienic system. Any relapse, or succeeding illness, will be avoided by continuing the packs for four to six weeks after the disease has been cured, applying them during the night and at first also during the day-time, from two to three hours.