The writing in the original is on the outside of the last leaf, which is in fact the cover. The front cover, if there ever was one, is lost. The ink with which the line containing the symbols is written corresponds with that in the body of the manuscript; and the line itself is placed symmetrically in the middle of the page, near the top. The two lower lines are apparently by another hand, probably of later date, certainly in ink of a different colour, and paler. The word "Philosophy" is in Bacon's own hand, written lightly in the upper corner at the left, and is no doubt merely a docket inserted afterwards when he was sorting his papers. What connexion there was between the note and the manuscript it is impossible to say. But it is evidently a careful memorandum of something, set down by somebody when the manuscript was at hand; and so many of the characters resemble those adopted to represent the planets and the signs of the zodiac, that one is led to suspect in it a note of the positions of the heavenly bodies at the time of some remarkable accident;--perhaps the plague, of which 30,578 persons died in London, during the year ending 22nd December, 1603. The period of the commencement, the duration, or the cessation of such an epidemic might naturally be so noted. Now three of the characters clearly represent respectively Mercury, Aquarius, and Sagittarius. The sign for Jupiter, as we find it in old books, is so like a 4, that the first figure of 45 may very well have been meant for it. The monogram at the beginning of the line bears a near resemblance to the sign of Capricorn in its most characteristic feature. And the mark over the sign of Aquarius appears to be an abbreviation of that which usually represents the Sun. (The blot between 1603 and B is nothing; being only meant to represent a figure 6 blotted out with the finger before the ink was dry.) Suspecting therefore that the writing contained a note of the positions of Mercury and Jupiter in the year 1603, I sent a copy to a scientific friend and asked him if from such data he could determine the month indicated. He found upon a rough calculation (taking account of mean motions only) that Jupiter did enter the sign of Sagittarius about the 10th of August, 1603, and continued there for about a twelvemonth; that the Sun entered Aquarius about the 12th or 13th of January, 1603-4; and that Mercury was about the 16th or 17th of the same month in the 26th or 27th degree of Capricorn: --coincidences which would have been almost conclusive as to the date indicated, if Capricorn had only stood where Aquarius does, and vice versa. But their position as they actually stood in the manuscript is a formidable, if not fatal, objection to the interpretation.